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心房颤动与心力衰竭双重流行的治疗考量

Treatment Considerations for a Dual Epidemic of Atrial Fibrillation and Heart Failure.

作者信息

Sharma Parikshit S, Callans David J

机构信息

Dr. Sharma- Cardiology Fellow, Wright Center for Graduate Medical Education, Scranton, PA; Associate Professor of Medicine, The Commonwealth Medical College, Scranton, PA.Dr. Callans- Professor of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA.

出版信息

J Atr Fibrillation. 2013 Aug 31;6(2):740. doi: 10.4022/jafib.740. eCollection 2013 Aug-Sep.

Abstract

Atrial fibrillation (AF) and heart failure (HF) have emerged as major cardiovascular epidemics in developed nations over the past decade. They share similar risk factors, seem to mutually accelerate progression and are associated with increased morbidity and mortality. Their relationship involves complex hemodynamic, neuro-hormonal, inflammatory and electrophysiologic mechanisms, which go beyond just mutual risk factors. This review focuses on updates in AF and HF with a hope of better understanding this relationship and the management of this complex duo.

摘要

在过去十年中,心房颤动(AF)和心力衰竭(HF)已成为发达国家主要的心血管流行病。它们具有相似的危险因素,似乎相互加速病情进展,且与发病率和死亡率增加相关。它们之间的关系涉及复杂的血流动力学、神经激素、炎症和电生理机制,这不仅仅是共同的危险因素。本综述重点关注心房颤动和心力衰竭的最新进展,以期更好地理解这种关系以及对这一复杂组合的管理。

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本文引用的文献

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Dronedarone in high-risk permanent atrial fibrillation.盐酸决奈达隆治疗高危持续性心房颤动
N Engl J Med. 2011 Dec 15;365(24):2268-76. doi: 10.1056/NEJMoa1109867. Epub 2011 Nov 14.
4
Atrial fibrillation and mortality in heart failure: a community study.心房颤动与心力衰竭患者的死亡率:一项社区研究。
Circ Heart Fail. 2011 Nov;4(6):740-6. doi: 10.1161/CIRCHEARTFAILURE.111.962688. Epub 2011 Sep 15.
8
Irbesartan in patients with atrial fibrillation.厄贝沙坦治疗心房颤动患者。
N Engl J Med. 2011 Mar 10;364(10):928-38. doi: 10.1056/NEJMoa1008816.

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