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机器人辅助肾上腺切除术:适应症与缺点

Robot-assisted adrenalectomy: indications and drawbacks.

作者信息

Nomine-Criqui C, Germain A, Ayav A, Bresler L, Brunaud L

机构信息

Department of Digestive, Hepatobiliary, Endocrine, and Oncology Surgery, University of Lorraine, CHU Nancy-Brabois (Adultes), 54511, Vandoeuvre-Les-Nancy, France.

Unité INSERM U954, Faculté de Médecine, University of Lorraine, 54511, Vandoeuvre-Les-Nancy, France.

出版信息

Updates Surg. 2017 Jun;69(2):127-133. doi: 10.1007/s13304-017-0448-6. Epub 2017 May 12.

DOI:10.1007/s13304-017-0448-6
PMID:28497219
Abstract

Adrenal tumors can vary from a benign adrenocortical adenoma with no hormonal secretion to a secretory adrenocortical malignancy (adrenocortical carcinoma) or a hormone-secreting tumor of the adrenal medulla (pheochromocytoma). Currently, laparoscopic adrenalectomy is regarded as the preferred surgical approach for the management of most adrenal surgical disorders, although there are no prospective randomized trials comparing this technique with open adrenalectomy. However, widespread adoption of robotic technology has positioned robotic adrenalectomy as an option in some medical centers. Speculative advantages associated with the use of the robotic system have rarely been evaluated in clinical settings and cost increase remains an important drawback associated with robotic surgery. This review summarizes current available data regarding robotic transperitoneal adrenalectomy including its indications, advantages, limitations, and comparison with conventional laparoscopic adrenalectomy. We believe that the use of a robotic system seems to be useful especially in more difficult patients with larger tumors, truncal paragangliomas, and bilateral and/or partial adrenalectomies. Overall, we believe that overcosts due to robotic system use could be balanced by hospital stay decrease, patients' referral increase, improved postoperative outcomes in more difficult patients and ergonomics for the surgeon. However, we also believe that the current surgical intuitive business model is counterproductive, because there are no available strong clinical data that could balance overcosts associated with the use of the robotic system.

摘要

肾上腺肿瘤的范围很广,从无激素分泌的良性肾上腺皮质腺瘤到分泌性肾上腺皮质恶性肿瘤(肾上腺皮质癌)或肾上腺髓质的激素分泌肿瘤(嗜铬细胞瘤)。目前,腹腔镜肾上腺切除术被视为治疗大多数肾上腺外科疾病的首选手术方法,尽管尚无前瞻性随机试验将该技术与开放性肾上腺切除术进行比较。然而,机器人技术的广泛应用使机器人肾上腺切除术在一些医疗中心成为一种选择。与使用机器人系统相关的推测性优势在临床环境中很少得到评估,而且成本增加仍然是机器人手术的一个重要缺点。本综述总结了目前关于机器人经腹肾上腺切除术的可用数据,包括其适应证、优势、局限性以及与传统腹腔镜肾上腺切除术的比较。我们认为,机器人系统的使用似乎特别有助于治疗病情更复杂的患者,如肿瘤较大的患者、躯干副神经节瘤患者以及需要进行双侧和/或部分肾上腺切除术的患者。总体而言,我们认为,使用机器人系统导致的成本过高可以通过缩短住院时间、增加患者转诊、改善病情更复杂患者的术后结果以及提高外科医生的操作舒适度来平衡。然而,我们也认为,目前的手术直观商业模式适得其反,因为没有有力的临床数据能够平衡与使用机器人系统相关的成本过高问题。

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Robotic assisted adrenalectomy: Is it ready for prime time?机器人辅助肾上腺切除术:它准备好进入黄金时代了吗?
Investig Clin Urol. 2016 Dec;57(Suppl 2):S130-S146. doi: 10.4111/icu.2016.57.S2.S130. Epub 2016 Nov 30.
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Risk factors for complications after adrenalectomy: results from a comprehensive national database.肾上腺切除术后并发症的危险因素:来自全国综合数据库的结果
Langenbecks Arch Surg. 2017 Mar;402(2):315-322. doi: 10.1007/s00423-016-1535-8. Epub 2016 Nov 28.
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A prospective study of 100 roboticallyassisted laparoscopic adrenalectomies.
Robotic-assisted versus laparoscopic adrenalectomy for large adrenal tumors: a systematic review and meta-analysis.
机器人辅助与腹腔镜肾上腺切除术治疗大型肾上腺肿瘤:一项系统评价和荟萃分析。
Int Urol Nephrol. 2025 Mar 12. doi: 10.1007/s11255-025-04442-0.
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Robotic Adrenalectomy and Clevidipine: A New Frontier in Pheochromocytoma Management Preliminary Study.机器人肾上腺切除术与克利夫地平:嗜铬细胞瘤治疗新前沿的初步研究
J Clin Med. 2025 Feb 9;14(4):1103. doi: 10.3390/jcm14041103.
5
Synchronous transperitoneal robotic-assisted bilateral cortical-sparing adrenalectomy for pheochromocytomas in a patient with multiple endocrine neoplasia type 2a (MEN2A) syndrome: a case report.同步经腹机器人辅助双侧保留皮质肾上腺切除术治疗2a型多发性内分泌腺瘤病(MEN2A)综合征患者的嗜铬细胞瘤:一例报告
Gland Surg. 2024 Dec 31;13(12):2430-2437. doi: 10.21037/gs-24-371. Epub 2024 Dec 27.
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Robotic posterior retroperitoneal adrenalectomy versus laparoscopic posterior retroperitoneal adrenalectomy: outcomes from a pooled analysis.机器人后腹腔镜肾上腺切除术与腹腔镜后腹腔镜肾上腺切除术:汇总分析结果。
Front Endocrinol (Lausanne). 2023 Nov 28;14:1278007. doi: 10.3389/fendo.2023.1278007. eCollection 2023.
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Minimally Invasive and Open Gastrectomy for Gastric Cancer: A Systematic Review and Network Meta-Analysis of Randomized Clinical Trials.微创与开放胃癌根治术治疗胃癌的系统评价和网状 Meta 分析。
Ann Surg Oncol. 2023 Sep;30(9):5544-5557. doi: 10.1245/s10434-023-13654-6. Epub 2023 Jun 1.
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Comparing surgical outcomes of approaches to adrenalectomy - a systematic review and network meta-analysis of randomised clinical trials.比较不同肾上腺切除术入路的手术效果 - 一项随机临床试验的系统回顾和网络荟萃分析。
Langenbecks Arch Surg. 2023 May 5;408(1):180. doi: 10.1007/s00423-023-02911-7.
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Updates Surg. 2023 Jan;75(1):217-225. doi: 10.1007/s13304-022-01410-6. Epub 2022 Nov 4.
一项对100例机器人辅助腹腔镜肾上腺切除术的前瞻性研究。
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Impact of novel techniques on minimally invasive adrenal surgery: trends and outcomes from a contemporary international large series in urology.新技术对微创肾上腺手术的影响:来自当代国际大型泌尿外科系列研究的趋势与结果
World J Urol. 2016 Oct;34(10):1473-9. doi: 10.1007/s00345-016-1791-9. Epub 2016 Feb 29.
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J Surg Oncol. 2015 Sep;112(3):305-9. doi: 10.1002/jso.23960. Epub 2015 Jul 15.
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