使用适配体封端的介孔二氧化硅纳米颗粒对致癌双酚A进行荧光传感
Fluorogenic Sensing of Carcinogenic Bisphenol A using Aptamer-Capped Mesoporous Silica Nanoparticles.
作者信息
Ribes Àngela, Aznar Elena, Bernardos Andrea, Marcos M Dolores, Amorós Pedro, Martínez-Máñez Ramón, Sancenón Félix
机构信息
Instituto Interuniversitario de Investigación de Reconocimiento MolecularyDesarrollo Tecnológico (IDM)., Universitat Politècnica de València, Universitat de València, Camí de Vera s/N, 46022, Valencia, Spain.
CIBER de Bioingeniería, BiomaterialesyNanomedicina (CIBER-BBN).
出版信息
Chemistry. 2017 Jun 27;23(36):8581-8584. doi: 10.1002/chem.201701024. Epub 2017 Jun 5.
Mesoporous silica nanoparticles loaded with rhodamine B and capped with a bisphenol A aptamer were used for the selective and sensitive detection of this lethal chemical. The pores of the nanoparticles are selectively opened in the presence of bisphenol A (through its selective coordination with the aptamer) with subsequent rhodamine B delivery. With this capped material a limit of detection as low as 3.5 μm of bisphenol A was measured.
负载若丹明B并以双酚A适配体封端的介孔二氧化硅纳米颗粒被用于对这种致命化学物质进行选择性和灵敏的检测。在双酚A存在的情况下（通过其与适配体的选择性配位作用），纳米颗粒的孔隙会被选择性地打开，随后释放出若丹明B。使用这种封端材料测得双酚A的检测限低至3.5 μm。
Zotero 插件