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青光眼滤过术后与视力相关的生活质量

Vision-related quality of life following glaucoma filtration surgery.

作者信息

Hirooka Kazuyuki, Nitta Eri, Ukegawa Kaori, Tsujikawa Akitaka

机构信息

Department of Ophthalmology, Kagawa University Faculty of Medicine, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan.

出版信息

BMC Ophthalmol. 2017 May 12;17(1):66. doi: 10.1186/s12886-017-0466-7.

Abstract

BACKGROUND

To evaluate vision-related quality of life (VR-QOL) following glaucoma filtration surgery.

METHODS

A total of 103 glaucoma patients scheduled to undergo glaucoma filtration surgery. Prior to and at three months after glaucoma filtration surgery, trabeculectomy or EX-PRESS, all patients completed the 25-item National Eye Institute Visual Function Questionnaire (VFQ-25). A total of 48 patients underwent combined cataract and filtration surgery. The clinical data collected pre- and postoperatively included best-corrected visual acuity (BCVA) and intraocular pressure (IOP).

RESULTS

The IOP decreased significantly from 19.0 ± 8.1 mmHg to 9.7 ± 3.9 mmHg (P < 0.001). Preoperative VFQ-25 composite score (65.8 ± 15.6) was similar to the postoperative score (67.8 ± 16.6). A significantly improved VFQ-25 composite score (pre: 63.2 ± 17.1, post: 67.7 ± 17.8; P = 0.001) was observed in the patients who underwent combined cataract and filtration surgery. There was a significant association between the BCVA changes in the operated eye and the changes in the VFQ-25 composite score (r = -0.315, P = 0.003).

CONCLUSIONS

Although glaucoma filtration surgery by itself did not decrease the VR-QOL in glaucoma patients, there was significant improvement in the VR-QOL after the patients underwent combined cataract and glaucoma filtration surgery.

摘要

背景

评估青光眼滤过术后与视力相关的生活质量(VR-QOL)。

方法

共有103例计划接受青光眼滤过手术的青光眼患者。在青光眼滤过手术(小梁切除术或EX-PRESS植入术)前及术后三个月,所有患者均完成了25项美国国立眼科研究所视觉功能问卷(VFQ-25)。共有48例患者接受了白内障联合滤过手术。术前和术后收集的临床数据包括最佳矫正视力(BCVA)和眼压(IOP)。

结果

眼压从19.0±8.1 mmHg显著降至9.7±3.9 mmHg(P<0.001)。术前VFQ-25综合评分(65.8±15.6)与术后评分(67.8±16.6)相似。接受白内障联合滤过手术的患者VFQ-25综合评分有显著改善(术前:63.2±17.1,术后:67.7±17.8;P = 0.001)。手术眼的BCVA变化与VFQ-25综合评分变化之间存在显著相关性(r = -0.315,P = 0.003)。

结论

尽管青光眼滤过手术本身并未降低青光眼患者的VR-QOL,但患者接受白内障联合青光眼滤过手术后,VR-QOL有显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/894b/5429566/ef85c8106a19/12886_2017_466_Fig1_HTML.jpg

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