Qi Peng, Zhang Dun, Wan Yi
Key Laboratory of Marine Environmental Corrosion and Bio-fouling, Institute of Oceanology, Chinese Academy of Sciences, 7 Nanhai Road, Qingdao 266071, China.
Key Laboratory of Marine Environmental Corrosion and Bio-fouling, Institute of Oceanology, Chinese Academy of Sciences, 7 Nanhai Road, Qingdao 266071, China.
Talanta. 2017 Aug 1;170:173-179. doi: 10.1016/j.talanta.2017.03.093. Epub 2017 Mar 30.
In this work, we discovered the morphology transformation property of polydopamine (PDA) nanomaterials, the addition of Fe initiated the dramatic morphology transformation of PDA dots from aggregated plate-like to uniform willow-leaf-like morphology. Further study revealed that this fascinating morphology transformation process could be attributed to the oxidative nature and coordination characteristic of Fe. This is the first report on the morphology transformation ability of PDA, and a probable self-assembled mechanism was proposed to explain this issue. Besides, we noticed that morphological and fluorescent properties of PDA dots were closely related, thus a fluorescent Fe detection method was presented based on the morphology-tunable PDA dots. With the proposed method, selective Fe detection was achieved with a wide linear dynamic range of 10μM to 1mM. Furthermore, since the morphology tuning behavior of PDA dots was easy to operate, we anticipate this ability will find significant utility in sensing, drug delivery, and tissue engineering.
在这项工作中，我们发现了聚多巴胺（PDA）纳米材料的形态转变特性，铁的加入引发了PDA点从聚集的板状到均匀的柳叶状的显著形态转变。进一步的研究表明，这种引人入胜的形态转变过程可归因于铁的氧化性质和配位特性。这是关于PDA形态转变能力的首次报道，并提出了一种可能的自组装机制来解释这个问题。此外，我们注意到PDA点的形态和荧光性质密切相关，因此基于形态可调的PDA点提出了一种荧光铁检测方法。利用所提出的方法，实现了选择性铁检测，线性动态范围宽，为10μM至1mM。此外，由于PDA点的形态调节行为易于操作，我们预计这种能力将在传感、药物递送和组织工程中找到重要应用。
