子痫前期患者血清内脂素水平的改变

Alteration of serum adropin level in preeclampsia.

作者信息

Wang Huihua, Gao Bo, Wu Zaigui, Wang Hanzhi, Dong Minyue

机构信息

Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Key Laboratory of Women's Reproductive Health of Zhejiang Province, China; Key Laboratory of Reproductive Genetics of the Ministry of Education, China.

出版信息

Pregnancy Hypertens. 2017 Apr;8:6-8. doi: 10.1016/j.preghy.2017.02.003. Epub 2017 Mar 1.

DOI:10.1016/j.preghy.2017.02.003

PMID:28501281

Abstract

To clarify the alterations in serum adropin and preptin concentrations in preeclampsia, we determined serum adropin and preptin levels in 29 women with normal pregnancy and 32 women with preeclampsia. We found that maternal age, body mass index and fetal gender were not significantly different between two groups; however, blood pressure, gestational age and neonatal birth weight were significantly different. Serum adropin levels were significantly increased in women with preeclampsia compared with those with normal pregnancy but there were no significant differences in preptin levels. An increase in maternal serum adropin level was found in preeclampsia, and this may be a compensation for pregnancy complicated with preeclampsia.

摘要

为了阐明子痫前期患者血清内脂素和前ptin浓度的变化，我们测定了29例正常妊娠妇女和32例子痫前期妇女的血清内脂素和前ptin水平。我们发现两组之间的产妇年龄、体重指数和胎儿性别无显著差异；然而，血压、孕周和新生儿出生体重有显著差异。与正常妊娠妇女相比，子痫前期妇女的血清内脂素水平显著升高，但前ptin水平无显著差异。子痫前期患者母体血清内脂素水平升高，这可能是对妊娠合并子痫前期的一种代偿。