Wescott Lindsay, Laskofski Michael, Senator Donna, Curran Carly
Office of Sponsored Programs, George Mason University, 4400 University Dr., 141 Research I, MS4C6, Fairfax, VA, 22030, USA.
Methods Mol Biol. 2017;1606:367-378. doi: 10.1007/978-1-4939-6990-6_24.
All investigators face the same challenge-the highly competitive nature of the grant review process. Innovation alone is not enough to ensure grant-supported funding. Applied clinical research requires a diverse, collaborative team of investigators with specialized skills, a supportive clinical research environment, and access to clinical material. Additionally, the lack of animal models for many diseases and ethical limitations prevent direct mechanistic experiments that are possible using in vitro systems or animal models. Therefore, specific granting mechanisms and program initiatives target translational research studies. This chapter provides grant writing tips and lists resources that may prove helpful for new investigators seeking research funding in support of translational research, biobanking, and research utilizing molecular biomarkers.
所有研究人员都面临着同样的挑战——拨款评审过程的高度竞争性。仅凭创新不足以确保获得拨款资助。应用临床研究需要一个由具备专业技能的研究人员组成的多元化协作团队、一个支持性的临床研究环境以及获取临床材料的途径。此外，许多疾病缺乏动物模型以及伦理限制阻碍了使用体外系统或动物模型进行的直接机制实验。因此，特定的拨款机制和项目倡议针对转化研究。本章提供了撰写拨款申请的技巧，并列出了一些资源，这些资源可能对寻求研究资金以支持转化研究、生物样本库建设以及利用分子生物标志物进行研究的新研究人员有所帮助。
