Borade Amrut, Kempegowda Harish, Maniar Hemil H, De Giacomo Anthony, Tornetta Paul, Bramlett Kasey, Marcantonio Andrew J, Marchand Lucas S, Kubiak Erik N, Ip William H, Kellam James F, Bender Jay S, Meinberg Eric G, Kee James, Renard Regis, Suk Michael, Horwitz Daniel S
Department of Orthopaedic Surgery, Geisinger Medical Center, Danville, PA, USA.
Department of Orthopaedic Surgery, Boston University Medical Center, Boston, MA, USA.
Injury. 2017 Jul;48(7):1594-1596. doi: 10.1016/j.injury.2017.04.051. Epub 2017 Apr 26.
On evaluation of the clinical indications of computed tomography (CT) scan of head in the patients with low-energy geriatric hip fractures, Maniar et al. identified physical evidence of head injury, new onset confusion, and Glasgow Coma Scale (GCS)<15 as predictive risk factors for acute findings on CT scan. The goal of the present study was to validate these three criteria as predictive risk factors for a larger population in a wider geographical distribution.
Patients ≥65 years of age with low-energy hip fractures from 6 trauma centers in a wide geographical distribution in the United States were included in this study. In addition to the relevant patient demographic findings, the above mentioned three criteria and acute findings on head CT scan were gathered as categorical variables.
In total 799 patients from 6 centers were included in the study. There were 67 patients (8.3%) with positive acute findings on head CT scan. All of these patients (100%) had at least one criteria positive. There were 732 patients who had negative acute findings on head CT scan with 376 patients (51%) having at least one criteria positive and 356 patients (49%) having no criteria positive. Sensitivity of 100% and negative predictive value of 100% was observed to predict negative acute findings on head CT scan when all the three criteria were negative.
With the observed 100% sensitivity and 100% negative predictive value, physical evidence of acute head injury, acute retrograde amnesia, and GCS<15 can be recommended as a clinical decision guide for the selective use of head CT scans in geriatric patients with low energy hip fractures. All the patients with positive acute head CT findings can be predicted in the presence of at least one positive criterion. In addition, if these criteria are used as a pre-requisite to order the head CT, around 50% of the unnecessary head CT scans can be avoided.
在评估低能量老年髋部骨折患者头部计算机断层扫描(CT)的临床指征时,马尼亚尔等人确定头部损伤的体格检查证据、新发意识模糊以及格拉斯哥昏迷量表(GCS)评分<15为CT扫描急性发现的预测风险因素。本研究的目的是在更广泛的地理分布范围内,针对更多人群验证这三个标准作为预测风险因素的有效性。
本研究纳入了来自美国广泛地理分布区域内6个创伤中心的65岁及以上低能量髋部骨折患者。除了相关的患者人口统计学数据外,上述三个标准以及头部CT扫描的急性发现均作为分类变量收集。
本研究共纳入了来自6个中心的799例患者。67例(8.3%)患者头部CT扫描有急性阳性发现。所有这些患者(100%)至少有一项标准呈阳性。732例患者头部CT扫描急性发现为阴性,其中376例(51%)至少有一项标准呈阳性,356例(49%)无标准呈阳性。当所有三项标准均为阴性时,预测头部CT扫描急性阴性发现的敏感性为100%,阴性预测值为100%。
鉴于观察到的100%敏感性和100%阴性预测值,急性头部损伤的体格检查证据、急性逆行性遗忘以及GCS<15可作为临床决策指南,用于指导低能量髋部骨折老年患者选择性进行头部CT扫描。所有头部CT急性阳性发现的患者在至少有一项阳性标准时均可被预测。此外,如果将这些标准用作开具头部CT检查的先决条件,大约50%的不必要头部CT扫描可以避免。