嗜酸性胃肠道疾病
Eosinophilic Gastrointestinal Disorders.
作者信息
Fahey Lisa M, Liacouras Chris A
机构信息
Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, 7NW, Philadelphia, PA 19104, USA; Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, 7NW, Philadelphia, PA 19104, USA; Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
出版信息
Pediatr Clin North Am. 2017 Jun;64(3):475-485. doi: 10.1016/j.pcl.2017.01.009.
Eosinophilic esophagitis (EoE) is an atopic disease that is characterized by an isolated infiltration of eosinophils into the epithelium of the esophagus and is triggered by specific allergens. Patients should undergo an upper endoscopy with biopsy after 6 to 8 weeks of treatment with a proton pump inhibitor in order to make the diagnosis of EoE. Eosinophilic gastroenteritis is a pathologic eosinophilic infiltration of any portion of the gastrointestinal tract, and eosinophilic proctocolitis is an eosinophilic infiltration in the colon alone.
嗜酸性食管炎（EoE）是一种特应性疾病，其特征是嗜酸性粒细胞单独浸润食管上皮，并由特定过敏原引发。患者在用质子泵抑制剂治疗6至8周后应接受上消化道内镜检查并活检，以便诊断嗜酸性食管炎。嗜酸性胃肠炎是胃肠道任何部位的病理性嗜酸性粒细胞浸润，而嗜酸性直肠结肠炎是仅在结肠的嗜酸性粒细胞浸润。
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