小肠结肠炎耶尔森菌肠炎所致反应性关节炎。
Reactive Arthritis Caused by Yersinia enterocolitica Enteritis.
作者信息
Honda Kazuya, Iwanaga Nozomi, Izumi Yasumori, Tsuji Yoshika, Kawahara Chieko, Michitsuji Toru, Higashi Shuntaro, Kawakami Atsushi, Migita Kiyoshi
机构信息
Department of Rheumatology and General Internal Medicine, Nagasaki Medical Center, Japan.
Department of Gastroenterology, Nagasaki Medical Center, Japan.
出版信息
Intern Med. 2017;56(10):1239-1242. doi: 10.2169/internalmedicine.56.7888. Epub 2017 May 15.
We report a case of reactive arthritis (ReA) triggered by Yersinia enterocolitica enteritis. A 24-year-old Japanese man developed polyarthritis in the lower limbs. Two weeks prior to these symptoms, he noted diarrhea, right lower abdominal pain and a fever. Y. enterocolitica was not isolated from a stool culture; however, he was diagnosed with ReA based on the colonoscopic findings of a high anti-Y. enterocolitica antibody titer and HLA-B27 antigen positivity. Following treatment with methotrexate and steroids, his arthritis improved. This is the first reported Japanese case of ReA in the English literature after a gastrointestinal infection caused by Y. enterocolitica.
我们报告一例由小肠结肠炎耶尔森菌肠炎引发的反应性关节炎（ReA）病例。一名24岁的日本男性出现下肢多关节炎。在这些症状出现前两周，他出现腹泻、右下腹疼痛和发热。粪便培养未分离出小肠结肠炎耶尔森菌；然而，根据结肠镜检查结果、高抗小肠结肠炎耶尔森菌抗体滴度以及HLA - B27抗原阳性，他被诊断为ReA。接受甲氨蝶呤和类固醇治疗后，他的关节炎有所改善。这是英文文献中首次报道的日本小肠结肠炎耶尔森菌引起胃肠道感染后发生ReA的病例。
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