躁狂是情绪的“高血压”吗？关于一种假说的探讨。
Is Mania the Hypertension of the Mood? Discussion of A Hypothesis.
作者信息
Rihmer Zoltán, Gonda Xénia, Döme Péter
机构信息
Department of Clinical and Theoretical Mental Health, Semmelweis University, Budapest, Hungary, and Laboratory of Suicide Research and Prevention, National Institute for Psychiatry and Addictions, Budapest, Hungary.
出版信息
Curr Neuropharmacol. 2017 Apr;15(3):424-433. doi: 10.2174/1570159X14666160902145635.
Beyond both being biphasic/bidirectional disorders (hypo)mania and essential hypertension share a surprising number of similarities and an overlap between their genetics, biological background, underlying personality and temperamental factors, precipitating factors, comorbidity and response to treatment, indicating a possibly partially shared biological background. Based on theoretical knowledge, similarities related to characteristics, manifestation and course, and the results of pharmacological studies related to the effects and side effects of pharmacotherapies used in the treatment of these two distinct disorders, the authors outline a hypothesis discussing the similar origins of these two phenomena and thus mania being the hypertension of mood in memory of Athanasios Koukopoulos, one of the greatest researchers and theoreticists of mania of all time.
除了都是双相/双向性疾病外，（轻）躁狂症和原发性高血压存在着惊人数量的相似之处，在遗传学、生物学背景、潜在人格和气质因素、诱发因素、合并症以及对治疗的反应方面存在重叠，这表明它们可能部分共享生物学背景。基于理论知识、与特征、表现和病程相关的相似性，以及与用于治疗这两种不同疾病的药物疗法的效果和副作用相关的药理学研究结果，作者概述了一个假说，讨论这两种现象的相似起源，因此将躁狂症称为情绪的高血压，以纪念有史以来最伟大的躁狂症研究者和理论家之一阿萨纳西奥斯·库科波洛斯。
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