O'Sullivan C C, Ruddy K J
Department of Medical Oncology, Rochester, Minnesota, 55905, United States of America.
Curr Breast Cancer Rep. 2016 Dec;8(4):183-192. doi: 10.1007/s12609-016-0229-0. Epub 2016 Oct 13.
Breast cancer is the most common non-cutaneous malignancy among women, and there are over 3 million breast cancer survivors living in the United States today. Excellent cure rates with modern therapies are associated with substantial toxicities for many women; it is important that health care providers attend to the resulting symptoms and issues to optimize quality of life in this population. In this article, we review management options for potential long term toxicities in breast cancer survivors, with a particular focus on bone health, fertility preservation, premature menopause, cardiac , and cognitive impairment.
乳腺癌是女性中最常见的非皮肤恶性肿瘤,目前美国有超过300万乳腺癌幸存者。现代疗法带来的高治愈率伴随着许多女性承受的巨大毒性;医疗保健提供者关注由此产生的症状和问题对于优化这一人群的生活质量非常重要。在本文中,我们回顾了乳腺癌幸存者潜在长期毒性的管理方案,特别关注骨骼健康、生育力保存、过早绝经、心脏和认知障碍。