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伊朗北部巴博勒乳糜胸的病因学研究方法

Etiological approach of chylothorax in Babol, northern Iran.

作者信息

Nikbakhsh Novin, Zamani Mohammad, Noorbaran Askari, Naghshineh Ali, Rastergar-Nejad Danial

机构信息

Cancer Research Center, Babol University of Medical Sciences, Babol, Iran.

Student Research Committee, Babol University of Medical Sciences, Babol, Iran.

出版信息

Caspian J Intern Med. 2017 Winter;8(1):30-34.

Abstract

BACKGROUND

Chylothorax results from leakage of lymph in the pleural cavity because of thoracic duct injury which is associated with severe metabolic disorders. The aim of this study was to evaluate the rate of chylothorax and its causes among hospitalized patients in Shahid Beheshti Hospital of Babol city, North of Iran.

METHODS

In this cross-sectional study, all patients with chylothorax admitted to the surgery department of Shahid Beheshti Hospital during 2002-2015 were included. Information including gender, age, duration of symptoms, laboratory findings, causes of disease and the type of treatment were extracted from the patients' records.

RESULTS

Of the 42 patients, 27 (64.3%) were men and 15 (35.7%) were women. The mean age of the study population was 51.03±16.95. The most common clinical symptoms were dyspnea (66.7%) and dyspnea with cough (21.4%), respectively. In all patients, the pleural fluid triglyceride level was greater than 110 mg/dl, whereas the presence of lymphatic in pleural fluid was eventful in 18 (42.8%) patients. The causes of the disease were traumatic (54.8%), non-traumatic (38.1%) and unknown (7.1%), which were not significantly correlated with gender. Nineteen (45.2%) patients were operated, 16 (38.1%) patients received supportive therapy, and 7 (16.7%) patients had the treatment of the underlying conditions and then supportive therapy.

CONCLUSION

According to the results, trauma was the most common cause of chylothorax. Therefore, identification and control of the traumatic factors seem to be the steps to prevent and reduce the chylothorax incidence and its complications.

摘要

背景

乳糜胸是由于胸导管损伤导致淋巴液漏入胸腔,常伴有严重的代谢紊乱。本研究旨在评估伊朗北部巴博勒市沙希德·贝赫什提医院住院患者中乳糜胸的发生率及其病因。

方法

在这项横断面研究中,纳入了2002年至2015年期间在沙希德·贝赫什提医院外科住院的所有乳糜胸患者。从患者记录中提取包括性别、年龄、症状持续时间、实验室检查结果、疾病病因和治疗类型等信息。

结果

42例患者中,27例(64.3%)为男性,15例(35.7%)为女性。研究人群的平均年龄为51.03±16.95岁。最常见的临床症状分别是呼吸困难(66.7%)和伴有咳嗽的呼吸困难(21.4%)。所有患者的胸腔积液甘油三酯水平均高于110mg/dl,而18例(42.8%)患者的胸腔积液中存在淋巴细胞。疾病病因包括创伤性(54.8%)、非创伤性(38.1%)和不明原因(7.1%),与性别无显著相关性。19例(45.2%)患者接受了手术治疗,16例(38.1%)患者接受了支持治疗,7例(16.7%)患者先治疗基础疾病然后接受支持治疗。

结论

根据研究结果,创伤是乳糜胸最常见的病因。因此,识别和控制创伤因素似乎是预防和减少乳糜胸发生率及其并发症的关键措施。

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