Andersen Morten Packert, Laub Michael, Biering-Sørensen Fin
Clinic for Spinal Cord Injuries, Rigshospitalet, Copenhagen, Denmark.
Respiratory Centre East, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Spinal Cord Ser Cases. 2017 Apr 27;3:17022. doi: 10.1038/scsandc.2017.22. eCollection 2017.
Comparable case series.
High-cervical spinal cord injury (SCI) may disrupt the ability to breathe sufficiently. To restore respiration a phrenic nerve pacer can be implanted. The aims of this study were to describe the use of phrenic nerve pacing in tetraplegics in Denmark and compare the users with a population of ventilator dependent tetraplegics.
Clinics for Spinal Cord Injuries, and Respiratory Centre East, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Nine tetraplegic individuals who had implantation of a phrenic nerve pacer and 16 home mechanical ventilator dependent tetraplegics met the inclusion criteria. Data were retrieved from medical records and a structured follow-up interview with seven individuals from each group.
No significant differences were found when comparing age at injury, time since injury, length of hospitalization, incidence of pneumonia, number of pneumonia hospitalizations, number of tracheal suctions, speech quality and activities of daily living or quality of life. On the Short Form Health Survey (SF36) mental health summary the median for both users of phrenic nerve pacing and users of mechanical ventilation was one s.d. above the mean of a standard population.
Nine people have had a phrenic nerve pacer implanted. They do not significantly differ from a group of home mechanical ventilator dependent tetraplegics on a number of performance measures, but both groups seem to have better quality of life than a standard population.
可比病例系列研究。
高位颈髓损伤(SCI)可能会破坏充分呼吸的能力。为恢复呼吸功能,可植入膈神经起搏器。本研究的目的是描述丹麦四肢瘫痪患者中膈神经起搏的使用情况,并将使用者与依赖呼吸机的四肢瘫痪患者群体进行比较。
丹麦哥本哈根大学 Rigshospitalet 脊髓损伤诊所和东部呼吸中心。
9 名植入膈神经起搏器的四肢瘫痪患者和 16 名依赖家用机械通气的四肢瘫痪患者符合纳入标准。数据从医疗记录以及对每组 7 名患者进行的结构化随访访谈中获取。
在比较受伤年龄、受伤时间、住院时间、肺炎发病率、肺炎住院次数、气管抽吸次数、语音质量、日常生活活动或生活质量时,未发现显著差异。在简短健康调查问卷(SF36)心理健康总结方面,膈神经起搏使用者和机械通气使用者的中位数均比标准人群均值高出一个标准差。
9 人植入了膈神经起搏器。在一些性能指标上,他们与依赖家用机械通气的四肢瘫痪患者群体没有显著差异,但两组的生活质量似乎都比标准人群更好。