• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

膈神经起搏与机械通气的比较。

Phrenic pacing compared with mechanical ventilation.

作者信息

Andersen Morten Packert, Laub Michael, Biering-Sørensen Fin

机构信息

Clinic for Spinal Cord Injuries, Rigshospitalet, Copenhagen, Denmark.

Respiratory Centre East, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

出版信息

Spinal Cord Ser Cases. 2017 Apr 27;3:17022. doi: 10.1038/scsandc.2017.22. eCollection 2017.

DOI:10.1038/scsandc.2017.22
PMID:28503328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5406928/
Abstract

STUDY DESIGN

Comparable case series.

OBJECTIVES

High-cervical spinal cord injury (SCI) may disrupt the ability to breathe sufficiently. To restore respiration a phrenic nerve pacer can be implanted. The aims of this study were to describe the use of phrenic nerve pacing in tetraplegics in Denmark and compare the users with a population of ventilator dependent tetraplegics.

SETTING

Clinics for Spinal Cord Injuries, and Respiratory Centre East, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

METHODS

Nine tetraplegic individuals who had implantation of a phrenic nerve pacer and 16 home mechanical ventilator dependent tetraplegics met the inclusion criteria. Data were retrieved from medical records and a structured follow-up interview with seven individuals from each group.

RESULTS

No significant differences were found when comparing age at injury, time since injury, length of hospitalization, incidence of pneumonia, number of pneumonia hospitalizations, number of tracheal suctions, speech quality and activities of daily living or quality of life. On the Short Form Health Survey (SF36) mental health summary the median for both users of phrenic nerve pacing and users of mechanical ventilation was one s.d. above the mean of a standard population.

CONCLUSIONS

Nine people have had a phrenic nerve pacer implanted. They do not significantly differ from a group of home mechanical ventilator dependent tetraplegics on a number of performance measures, but both groups seem to have better quality of life than a standard population.

摘要

研究设计

可比病例系列研究。

目的

高位颈髓损伤(SCI)可能会破坏充分呼吸的能力。为恢复呼吸功能,可植入膈神经起搏器。本研究的目的是描述丹麦四肢瘫痪患者中膈神经起搏的使用情况,并将使用者与依赖呼吸机的四肢瘫痪患者群体进行比较。

地点

丹麦哥本哈根大学 Rigshospitalet 脊髓损伤诊所和东部呼吸中心。

方法

9 名植入膈神经起搏器的四肢瘫痪患者和 16 名依赖家用机械通气的四肢瘫痪患者符合纳入标准。数据从医疗记录以及对每组 7 名患者进行的结构化随访访谈中获取。

结果

在比较受伤年龄、受伤时间、住院时间、肺炎发病率、肺炎住院次数、气管抽吸次数、语音质量、日常生活活动或生活质量时,未发现显著差异。在简短健康调查问卷(SF36)心理健康总结方面,膈神经起搏使用者和机械通气使用者的中位数均比标准人群均值高出一个标准差。

结论

9 人植入了膈神经起搏器。在一些性能指标上,他们与依赖家用机械通气的四肢瘫痪患者群体没有显著差异,但两组的生活质量似乎都比标准人群更好。

相似文献

1
Phrenic pacing compared with mechanical ventilation.膈神经起搏与机械通气的比较。
Spinal Cord Ser Cases. 2017 Apr 27;3:17022. doi: 10.1038/scsandc.2017.22. eCollection 2017.
2
Thirty-Six-Month Follow-up of Diaphragm Pacing with Phrenic Nerve Stimulation for Ventilator Dependence in Traumatic Tetraplegia: The Way Forward for Spinal Cord Injury Rehabilitation in a Developing Country.膈神经刺激膈肌起搏治疗创伤性四肢瘫呼吸机依赖的36个月随访:发展中国家脊髓损伤康复的前进方向
Asian Spine J. 2021 Dec;15(6):874-880. doi: 10.31616/asj.2020.0227. Epub 2020 Dec 28.
3
Phrenic nerve pacing via intramuscular diaphragm electrodes in tetraplegic subjects.通过膈肌肌内电极对四肢瘫痪患者进行膈神经起搏。
Chest. 2005 Feb;127(2):671-8. doi: 10.1378/chest.127.2.671.
4
Multicenter review of diaphragm pacing in spinal cord injury: successful not only in weaning from ventilators but also in bridging to independent respiration.脊髓损伤中膈神经刺激的多中心回顾:不仅有助于脱机,而且有助于向自主呼吸过渡,效果良好。
J Trauma Acute Care Surg. 2014 Feb;76(2):303-9; discussion 309-10. doi: 10.1097/TA.0000000000000112.
5
Neural prostheses in the respiratory system.呼吸系统中的神经假体。
J Rehabil Res Dev. 2001 Nov-Dec;38(6):601-7.
6
Restoration of respiratory muscle function following spinal cord injury. Review of electrical and magnetic stimulation techniques.脊髓损伤后呼吸肌功能的恢复。电刺激和磁刺激技术综述。
Respir Physiol Neurobiol. 2005 Jul 28;147(2-3):273-87. doi: 10.1016/j.resp.2005.03.007.
7
Phrenic nerve stimulation in the evaluation of ventilator-dependent individuals with C4- and C5-level spinal cord injury.膈神经刺激在评估C4和C5水平脊髓损伤的呼吸机依赖个体中的应用
Am J Phys Med Rehabil. 2007 Feb;86(2):153-7. doi: 10.1097/PHM.0b013e31802edce9.
8
Diaphragmatic reinnervation in ventilator-dependent patients with cervical spinal cord injury and concomitant phrenic nerve lesions using simultaneous nerve transfers and implantable neurostimulators.在依赖呼吸机的颈脊髓损伤并伴有膈神经损伤患者中,使用同步神经移植和植入式神经刺激器进行膈神经再支配。
J Reconstr Microsurg. 2015 Jun;31(5):391-5. doi: 10.1055/s-0035-1549159. Epub 2015 Apr 13.
9
Mapping the phrenic nerve motor point: the key to a successful laparoscopic diaphragm pacing system in the first human series.绘制膈神经运动点:首例人体系列中成功的腹腔镜膈神经起搏系统的关键。
Surgery. 2004 Oct;136(4):819-26. doi: 10.1016/j.surg.2004.06.030.
10
Diaphragm Pacing as a Rehabilitative Tool for Patients With Pompe Disease Who Are Ventilator-Dependent: Case Series.膈肌起搏作为依赖呼吸机的庞贝病患者的康复工具:病例系列
Phys Ther. 2016 May;96(5):696-703. doi: 10.2522/ptj.20150122. Epub 2016 Feb 18.

引用本文的文献

1
Mental health reported in adult invasive home mechanical ventilation through a tracheostomy: A scoping review.经气管造口进行成人有创家庭机械通气时的心理健康状况:一项范围综述
Int J Nurs Stud Adv. 2022 Nov 24;4:100110. doi: 10.1016/j.ijnsa.2022.100110. eCollection 2022 Dec.

本文引用的文献

1
Definitions of quality of life: what has happened and how to move on.生活质量的定义:已发生的情况及如何继续前行。
Top Spinal Cord Inj Rehabil. 2014 Summer;20(3):167-80. doi: 10.1310/sci2003-167.
2
International Spinal Cord Injury Quality of Life Basic Data Set.国际脊髓损伤生活质量基本数据集。
Spinal Cord. 2012 Sep;50(9):672-5. doi: 10.1038/sc.2012.27. Epub 2012 Mar 27.
3
International spinal cord injury pulmonary function basic data set.国际脊髓损伤肺功能基础数据集。
Spinal Cord. 2012 Jun;50(6):418-21. doi: 10.1038/sc.2011.183. Epub 2012 Jan 24.
4
Intrathoracic phrenic pacing: a 10-year experience in France.胸腔内膈神经起搏:法国 10 年经验。
J Thorac Cardiovasc Surg. 2011 Aug;142(2):378-83. doi: 10.1016/j.jtcvs.2011.04.033. Epub 2011 May 26.
5
Mechanical ventilation, health, and quality of life following spinal cord injury.脊髓损伤后的机械通气、健康和生活质量。
Arch Phys Med Rehabil. 2011 Mar;92(3):457-63. doi: 10.1016/j.apmr.2010.07.237.
6
Standardization of data analysis and reporting of results from the International Spinal Cord Injury Core Data Set.国际脊髓损伤核心数据集分析和结果报告的数据标准化。
Spinal Cord. 2011 May;49(5):596-9. doi: 10.1038/sc.2010.172. Epub 2010 Dec 7.
7
Phrenic nerve stimulation: the Australian experience.膈神经刺激:澳大利亚的经验。
J Clin Neurosci. 2010 Feb;17(2):205-8. doi: 10.1016/j.jocn.2009.06.012. Epub 2010 Jan 6.
8
Phrenic nerve stimulation in patients with spinal cord injury.膈神经刺激治疗脊髓损伤患者。
Respir Physiol Neurobiol. 2009 Nov 30;169(2):200-9. doi: 10.1016/j.resp.2009.09.008. Epub 2009 Sep 26.
9
Sleep disordered breathing following spinal cord injury.脊髓损伤后的睡眠呼吸障碍。
Respir Physiol Neurobiol. 2009 Nov 30;169(2):165-70. doi: 10.1016/j.resp.2009.08.014. Epub 2009 Sep 1.
10
Diaphragm pacing restores olfaction in tetraplegia.
Eur Respir J. 2009 Aug;34(2):365-70. doi: 10.1183/09031936.00177708. Epub 2009 Feb 27.