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膈神经起搏与机械通气的比较。

Phrenic pacing compared with mechanical ventilation.

作者信息

Andersen Morten Packert, Laub Michael, Biering-Sørensen Fin

机构信息

Clinic for Spinal Cord Injuries, Rigshospitalet, Copenhagen, Denmark.

Respiratory Centre East, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

出版信息

Spinal Cord Ser Cases. 2017 Apr 27;3:17022. doi: 10.1038/scsandc.2017.22. eCollection 2017.

Abstract

STUDY DESIGN

Comparable case series.

OBJECTIVES

High-cervical spinal cord injury (SCI) may disrupt the ability to breathe sufficiently. To restore respiration a phrenic nerve pacer can be implanted. The aims of this study were to describe the use of phrenic nerve pacing in tetraplegics in Denmark and compare the users with a population of ventilator dependent tetraplegics.

SETTING

Clinics for Spinal Cord Injuries, and Respiratory Centre East, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

METHODS

Nine tetraplegic individuals who had implantation of a phrenic nerve pacer and 16 home mechanical ventilator dependent tetraplegics met the inclusion criteria. Data were retrieved from medical records and a structured follow-up interview with seven individuals from each group.

RESULTS

No significant differences were found when comparing age at injury, time since injury, length of hospitalization, incidence of pneumonia, number of pneumonia hospitalizations, number of tracheal suctions, speech quality and activities of daily living or quality of life. On the Short Form Health Survey (SF36) mental health summary the median for both users of phrenic nerve pacing and users of mechanical ventilation was one s.d. above the mean of a standard population.

CONCLUSIONS

Nine people have had a phrenic nerve pacer implanted. They do not significantly differ from a group of home mechanical ventilator dependent tetraplegics on a number of performance measures, but both groups seem to have better quality of life than a standard population.

摘要

研究设计

可比病例系列研究。

目的

高位颈髓损伤(SCI)可能会破坏充分呼吸的能力。为恢复呼吸功能,可植入膈神经起搏器。本研究的目的是描述丹麦四肢瘫痪患者中膈神经起搏的使用情况,并将使用者与依赖呼吸机的四肢瘫痪患者群体进行比较。

地点

丹麦哥本哈根大学 Rigshospitalet 脊髓损伤诊所和东部呼吸中心。

方法

9 名植入膈神经起搏器的四肢瘫痪患者和 16 名依赖家用机械通气的四肢瘫痪患者符合纳入标准。数据从医疗记录以及对每组 7 名患者进行的结构化随访访谈中获取。

结果

在比较受伤年龄、受伤时间、住院时间、肺炎发病率、肺炎住院次数、气管抽吸次数、语音质量、日常生活活动或生活质量时,未发现显著差异。在简短健康调查问卷(SF36)心理健康总结方面,膈神经起搏使用者和机械通气使用者的中位数均比标准人群均值高出一个标准差。

结论

9 人植入了膈神经起搏器。在一些性能指标上,他们与依赖家用机械通气的四肢瘫痪患者群体没有显著差异,但两组的生活质量似乎都比标准人群更好。

相似文献

1
Phrenic pacing compared with mechanical ventilation.膈神经起搏与机械通气的比较。
Spinal Cord Ser Cases. 2017 Apr 27;3:17022. doi: 10.1038/scsandc.2017.22. eCollection 2017.

本文引用的文献

2
International Spinal Cord Injury Quality of Life Basic Data Set.国际脊髓损伤生活质量基本数据集。
Spinal Cord. 2012 Sep;50(9):672-5. doi: 10.1038/sc.2012.27. Epub 2012 Mar 27.
3
International spinal cord injury pulmonary function basic data set.国际脊髓损伤肺功能基础数据集。
Spinal Cord. 2012 Jun;50(6):418-21. doi: 10.1038/sc.2011.183. Epub 2012 Jan 24.
4
Intrathoracic phrenic pacing: a 10-year experience in France.胸腔内膈神经起搏:法国 10 年经验。
J Thorac Cardiovasc Surg. 2011 Aug;142(2):378-83. doi: 10.1016/j.jtcvs.2011.04.033. Epub 2011 May 26.
7
Phrenic nerve stimulation: the Australian experience.膈神经刺激:澳大利亚的经验。
J Clin Neurosci. 2010 Feb;17(2):205-8. doi: 10.1016/j.jocn.2009.06.012. Epub 2010 Jan 6.
8
Phrenic nerve stimulation in patients with spinal cord injury.膈神经刺激治疗脊髓损伤患者。
Respir Physiol Neurobiol. 2009 Nov 30;169(2):200-9. doi: 10.1016/j.resp.2009.09.008. Epub 2009 Sep 26.
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Sleep disordered breathing following spinal cord injury.脊髓损伤后的睡眠呼吸障碍。
Respir Physiol Neurobiol. 2009 Nov 30;169(2):165-70. doi: 10.1016/j.resp.2009.08.014. Epub 2009 Sep 1.
10
Diaphragm pacing restores olfaction in tetraplegia.
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