Clinical outcomes at one year following keratoconus treatment with accelerated transepithelial cross-linking.

This study evaluated the clinical outcomes in keratoconus corneas following accelerated transepithelial corneal collagen cross-linking (CXL) (Avedro KXL system, Waltham, MA, USA) over one year of follow-up. The mean depth of the demarcation line measured by optical coherence tomography (OCT) was 205.19 µm. One month after surgery, a non-statistically significant change was noted in sphere (=0.18) and in spherical equivalent (=0.17), whereas a significant improvement was observed in corrected distance visual acuity (=0.04). A significant change was observed in topographic astigmatism (=0.03) and posterior corneal a sphericity (=0.04). Accelerated transepithelial CXL may be a useful technique for the management of progressive keratoconus.