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序贯式角膜基质环植入术联合角膜交联术治疗患有春季角结膜炎的儿童圆锥角膜

Sequential Keraring implantation and corneal cross-linking for the treatment of keratoconus in children with vernal keratoconjunctivitis.

作者信息

Abozaid Mortada A

机构信息

Ophthalmology Department, Faculty of Medicine, Sohag University, Sohag, Egypt.

出版信息

Clin Ophthalmol. 2017 Oct 24;11:1891-1895. doi: 10.2147/OPTH.S150022. eCollection 2017.

Abstract

PURPOSE

The purpose of this study was to assess the safety and efficacy of femtosecond laser-assisted Keraring implantation followed by transepithelial accelerated corneal collagen cross-linking (CXL) for the treatment of keratoconus in children with vernal keratoconjunctivitis (VKC).

STUDY DESIGN

This is a prospective interventional non-comparative case series.

PATIENTS AND METHODS

Eighteen eyes of 11 children with keratoconus and VKC were included in this study. All the cases were treated with femtosecond laser-assisted Keraring implantation followed after 2 weeks by transepithelial accelerated CXL, and the patients were followed up for 1 year.

RESULTS

The preoperative mean uncorrected visual acuity (UCVA) was 1.01±0.2 (logMAR), whereas the postoperative mean UCVA was 0.6±0.2. The preoperative mean best-corrected visual acuity (BCVA) was 0.6±0.1, whereas the postoperative mean BCVA was 0.40±0.2. The preoperative average keratometry was 50.3±2.7 D, whereas the postoperative average keratometry was 45.8±3.1 D.

CONCLUSION

The results of this study suggest that femtosecond laser-assisted Keraring implantation followed by CXL is safe and effective in the management of keratoconus in children with VKC. However, studies with a longer follow-up period are needed.

摘要

目的

本研究旨在评估飞秒激光辅助植入Keraring后行上皮下加速角膜胶原交联(CXL)治疗春季角结膜炎(VKC)患儿圆锥角膜的安全性和有效性。

研究设计

这是一项前瞻性干预性非对照病例系列研究。

患者与方法

本研究纳入了11例患有圆锥角膜和VKC的儿童的18只眼。所有病例均接受飞秒激光辅助植入Keraring,2周后行上皮下加速CXL,并对患者进行了1年的随访。

结果

术前平均裸眼视力(UCVA)为1.01±0.2(logMAR),而术后平均UCVA为0.6±0.2。术前平均最佳矫正视力(BCVA)为0.6±0.1,而术后平均BCVA为0.40±0.2。术前平均角膜曲率为50.3±2.7 D,而术后平均角膜曲率为45.8±3.1 D。

结论

本研究结果表明,飞秒激光辅助植入Keraring后行CXL治疗VKC患儿圆锥角膜是安全有效的。然而,需要进行更长随访期的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e54/5661448/f78b0187df62/opth-11-1891Fig1.jpg

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