Abozaid Mortada A
Ophthalmology Department, Faculty of Medicine, Sohag University, Sohag, Egypt.
Clin Ophthalmol. 2017 Oct 24;11:1891-1895. doi: 10.2147/OPTH.S150022. eCollection 2017.
The purpose of this study was to assess the safety and efficacy of femtosecond laser-assisted Keraring implantation followed by transepithelial accelerated corneal collagen cross-linking (CXL) for the treatment of keratoconus in children with vernal keratoconjunctivitis (VKC).
This is a prospective interventional non-comparative case series.
Eighteen eyes of 11 children with keratoconus and VKC were included in this study. All the cases were treated with femtosecond laser-assisted Keraring implantation followed after 2 weeks by transepithelial accelerated CXL, and the patients were followed up for 1 year.
The preoperative mean uncorrected visual acuity (UCVA) was 1.01±0.2 (logMAR), whereas the postoperative mean UCVA was 0.6±0.2. The preoperative mean best-corrected visual acuity (BCVA) was 0.6±0.1, whereas the postoperative mean BCVA was 0.40±0.2. The preoperative average keratometry was 50.3±2.7 D, whereas the postoperative average keratometry was 45.8±3.1 D.
The results of this study suggest that femtosecond laser-assisted Keraring implantation followed by CXL is safe and effective in the management of keratoconus in children with VKC. However, studies with a longer follow-up period are needed.
本研究旨在评估飞秒激光辅助植入Keraring后行上皮下加速角膜胶原交联(CXL)治疗春季角结膜炎(VKC)患儿圆锥角膜的安全性和有效性。
这是一项前瞻性干预性非对照病例系列研究。
本研究纳入了11例患有圆锥角膜和VKC的儿童的18只眼。所有病例均接受飞秒激光辅助植入Keraring,2周后行上皮下加速CXL,并对患者进行了1年的随访。
术前平均裸眼视力(UCVA)为1.01±0.2(logMAR),而术后平均UCVA为0.6±0.2。术前平均最佳矫正视力(BCVA)为0.6±0.1,而术后平均BCVA为0.40±0.2。术前平均角膜曲率为50.3±2.7 D,而术后平均角膜曲率为45.8±3.1 D。
本研究结果表明,飞秒激光辅助植入Keraring后行CXL治疗VKC患儿圆锥角膜是安全有效的。然而,需要进行更长随访期的研究。