Chitsaz Ahmad, Ghorbani Abbas, Dashti Masoumeh, Khosravi Mohsen, Kianmehr Mohammadreza
Department of Neurology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Neurology, Mohammad Rasolalah Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2017 Apr 17;6:44. doi: 10.4103/2277-9175.204587. eCollection 2017.
Migraines are a neurological disease, of which the most common symptom is an intense and disabling episodic headache. Many persons experience sensory hyper excitability manifested by photophobia, phonophobia and osmophobia. This study was planned to investigate the prevalence of osmophobia in migranous and episodic tension type headache (ETTH).
A semi-structured questionnaire was administered to all patients to evaluate the eventual presence of osmophobia during a headache attack and different characteristics of osmophobia were determined.
Osmophobia reported in 84% with migranous headache with aura, 74% of migranous patients without aura and in 43.3% of those with ETTH. In 50% of patients, osmophobia was present in all of their headache attacks, 11.7% had osmophobia in more than half of their attacks (from 10 attacks they reported osmophobia in 5-9 ones) and others had this sign in less than half of their attacks (from 10 attacks they reported osmophobia in less than 5 ones). Most frequently the offending odors were scents (88%), foods (54.2%) and cigarette smoke (62.5%). Osmophobia starts 30 min before the headache starts in 22.7% of patients.
Osmophobia appears structurally integrated into the migraine history of the patient; however, for differential diagnosis with ETTH, other criteria are necessary.
偏头痛是一种神经系统疾病,其最常见的症状是剧烈且使人丧失能力的发作性头痛。许多人会经历由畏光、畏声和畏嗅表现出的感觉过敏。本研究旨在调查偏头痛和发作性紧张型头痛(ETTH)中畏嗅的患病率。
对所有患者进行半结构化问卷调查,以评估头痛发作期间畏嗅的最终存在情况,并确定畏嗅的不同特征。
有先兆偏头痛患者中84%报告有畏嗅,无先兆偏头痛患者中74%有畏嗅,ETTH患者中43.3%有畏嗅。50%的患者在所有头痛发作中都有畏嗅,11.7%的患者在超过一半的发作中有畏嗅(在他们报告的10次发作中,有5 - 9次有畏嗅),其他患者在不到一半的发作中有此症状(在他们报告的10次发作中,有不到5次有畏嗅)。最常见的刺激性气味是香水味(88%)、食物味(54.2%)和香烟烟雾味(62.5%)。22.7%的患者畏嗅在头痛开始前30分钟出现。
畏嗅在结构上似乎融入了患者的偏头痛病史;然而,对于与ETTH进行鉴别诊断,还需要其他标准。