Lv Hai-Ning, Zeng Ke-Wu, Zhao Ming-Bo, Jiang Yong, Tu Peng-Fei
a State Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences, Peking University , Beijing 100191 , China.
J Asian Nat Prod Res. 2018 Mar;20(3):195-200. doi: 10.1080/10286020.2017.1326910. Epub 2017 May 15.
Two pyrrolo[2,1-a]isoquinolines (1 and 2) and three pyrrole alkaloids (3-5), including three new ones, named sinopyrines A-C (1-3), were isolated from the 95% EtOH extract of the stems and rhizomes of Sinomenium acutum (Thumb.) Rehd. et Wils. The structures of the new compounds were elucidated on the basis of spectroscopic data. This is the first report of pyrrole-bearing natural compounds from the family Menispermaceae.
从青风藤（Sinomenium acutum (Thumb.) Rehd. et Wils.）的茎和根茎的95%乙醇提取物中分离出两种吡咯并[2,1-a]异喹啉（1和2）和三种吡咯生物碱（3-5），其中包括三种新的生物碱，命名为青藤碱A-C（1-3）。根据光谱数据阐明了新化合物的结构。这是防己科含吡咯天然化合物的首次报道。
