窄带成像技术在声带白斑诊断与治疗中的应用价值。
The usefulness of narrow-band imaging for the diagnosis and treatment of vocal fold leukoplakia.
作者信息
Huang Fang, Yu Jinchao, Zhang Fan, He Changding, Li Shimin, Shao Jun
机构信息
a Department of Otorhinolaryngology Heck and Neck Surgery , Eye, Ear, Nose & Throat Hospital, Fudan University , Shanghai , PR China.
b Department of Laser and Plastic Surgery , Eye, Ear, Nose & Throat Hospital, Fudan University , Shanghai , PR China.
出版信息
Acta Otolaryngol. 2017 Sep;137(9):1002-1006. doi: 10.1080/00016489.2017.1324216. Epub 2017 May 14.
OBJECTIVE
This research was aimed to explore the efficacy of narrow-band imaging (NBI) on distinguishing the degree of dysplasia of vocal fold leukoplakia.
METHODS
Patients were examined by flexible endoscopy, under white light endoscopy (WLE) and NBI. 78 lesions were divided into two groups according to the NBI classification. Group 1: non-dysplasia (ND), including squamous hyperplasia with hyperkeratosis or parakeratosis; Group 2: squamous hyperplasia with mild or moderate dysplasia (MD) or severe dysplasia (SD), or carcinoma in situ (CIS).
RESULTS
The diagnostic accuracy of NBI for Group 1 and Group 2 was 69.70% (23/33) and 95.56% (43/45), respectively, and the kappa index was 0.711 and a p value < .05, which was considered statistically significant.
CONCLUSIONS
The NBI could roughly estimate the degree of dysplasia. Differentiating between ND, MD, SD, and CIS, which may be useful for clinicians on selecting suitable therapies.
目的
本研究旨在探讨窄带成像（NBI）在区分声带白斑发育异常程度方面的疗效。
方法
对患者进行柔性内镜检查，包括白光内镜（WLE）和NBI。根据NBI分类将78个病变分为两组。第1组：无发育异常（ND），包括伴有角化过度或不全角化的鳞状上皮增生；第2组：伴有轻度或中度发育异常（MD）或重度发育异常（SD）或原位癌（CIS）的鳞状上皮增生。
结果
NBI对第1组和第2组的诊断准确率分别为69.70%（23/33）和95.56%（43/45），kappa指数为0.711，p值<0.05，差异具有统计学意义。
结论
NBI可大致评估发育异常程度，区分ND、MD、SD和CIS，这可能有助于临床医生选择合适的治疗方法。
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