Gröschl Michael
Celerion Switzerland AG, Allmendstrasse 32, CH-8320 Fehraltorf, Switzerland.
Bioanalysis. 2017 Apr;9(8):655-668. doi: 10.4155/bio-2017-0010. Epub 2017 May 15.
Saliva is gaining increasing attention as a bioanalytical sample matrix. Mostly because of the easy and noninvasive collection, it is not only beneficial in endocrinological and behavioral science, but also in pediatrics. Saliva also has the advantage of being the only body fluid which can be collected even during physical exercise, for example, during sportive activities, and there are physiological characteristics that make it superior to serum/plasma or urine for specific scientific questions. This review provides an insight into the physiology of saliva formation, explaining how certain compounds enter this bodily fluid, and gives advice for collection, storage and analytical methods. Finally, it presents a number of reliable and proven applications for saliva analysis from scientific fields including endocrinology, sports medicine, forensics and immunology.
唾液作为一种生物分析样本基质正受到越来越多的关注。主要由于其采集简便且无创，它不仅在内分泌学和行为科学中有益，在儿科学中也是如此。唾液还具有即使在体育锻炼期间，例如在体育活动期间也能采集的优势，并且具有一些生理特性，使其在特定科学问题上优于血清/血浆或尿液。本综述深入探讨了唾液形成的生理学，解释了某些化合物如何进入这种体液，并给出了采集、储存和分析方法的建议。最后，它展示了唾液分析在包括内分泌学、运动医学、法医学和免疫学等科学领域的一些可靠且经证实的应用。
