Komshian Sevan R, Lu Kimberly, Pike Steven L, Siracuse Jeffrey J
Division of Vascular and Endovascular Surgery, School of Medicine, Boston University Boston, MA, USA.
Vasc Health Risk Manag. 2017 May 8;13:161-168. doi: 10.2147/VHRM.S106898. eCollection 2017.
Infrainguinal arterial occlusive disease can lead to potentially disabling and limb-threatening conditions. Revascularization may be indicated for claudication, rest pain, or tissue loss. Although endovascular interventions are becoming more prevalent, open surgeries such as endarterectomy and bypass are still needed and performed regularly. Open reconstruction has been associated with postoperative morbidity, both at the local and at the systemic levels. Local complications include surgical site infections (SSIs 0-5.3%), graft failure (12-60%), and amputation (5.7-27%), and more systemic issues include cardiac (2.6-18.4%), respiratory (2.5%), renal (4%), neurovascular (1.5%), and thromboembolic (0.2-1%) complications. While such outcomes present an additional challenge to the postoperative management of surgical patients, it may be possible to minimize their occurrence through careful risk stratification and preoperative assessment. Therefore, individualized selection of candidates for open repair requires weighing the need for intervention against the likelihood of adverse outcomes based on preoperative risk factors. This review provides an overview of open reconstruction, focusing on identifying the clinical indications for surgery and perioperative morbidity and mortality.
腹股沟下动脉闭塞性疾病可导致潜在的致残和肢体威胁状况。对于间歇性跛行、静息痛或组织缺损,可能需要进行血运重建。尽管血管内介入治疗越来越普遍,但诸如动脉内膜切除术和旁路手术等开放手术仍然是必要的且经常进行。开放重建与术后局部和全身层面的发病率相关。局部并发症包括手术部位感染(0 - 5.3%)、移植物失败(12 - 60%)和截肢(5.7 - 27%),更多的全身问题包括心脏(2.6 - 18.4%)、呼吸(2.5%)、肾脏(4%)、神经血管(1.5%)和血栓栓塞(0.2 - 1%)并发症。虽然这些结果给手术患者的术后管理带来了额外挑战,但通过仔细的风险分层和术前评估,有可能将其发生率降至最低。因此,对于开放修复候选者的个体化选择需要根据术前风险因素,权衡干预需求与不良后果的可能性。本综述概述了开放重建,重点是确定手术的临床指征以及围手术期的发病率和死亡率。