Stevenson William G
Cardiac Arrhythmia Program, Brigham and Women's Hospital; Harvard Medical School, Boston, USA.
Arrhythm Electrophysiol Rev. 2017 Apr;6(1):18. doi: 10.15420/aer.2017.6.1:PP7.
In January 2017 we lost a giant in cardiac electrophysiology, whose work and teachings touched all of us working in the field. Mark Josephson's early work, building on the work of Hein Wellens in using programmed stimulation and catheter mapping to understand scar-related ventricular tachycardias, led the way to surgical and then catheter ablation as a viable therapy for that arrhythmia. His seminal observations are many and catalogued in 'The Josephson School' a wonderful book with 59 Chapters and extensive commentary devoted to his research.1 In the area of scar-related VT alone his work characterising electrograms in infarct scars and defining their relation to reentry circuits led to the development of substrate mapping techniques in common use today. His attention to the details of recording techniques helped establish the standards for electrophysiology studies. His investigational studies are not limited to ventricular arrhythmias but extend across the spectrum of cardiac electrophysiology. He was a superb observer with a talent for recognising subtle, unexpected events and delving deep to explore their potential mechanisms and significance.
2017年1月，我们失去了心脏电生理学领域的一位巨人，他的工作和教诲影响了我们所有从事该领域工作的人。马克·约瑟夫森早期的工作以海因·韦伦斯利用程控刺激和导管标测来理解瘢痕相关室性心动过速的工作为基础，引领了外科手术以及后来导管消融成为治疗该心律失常的可行疗法。他的开创性观察不胜枚举，都收录在《约瑟夫森学派》一书中，这是一本精彩的书籍，有59章以及大量专门论述他研究的评论。仅在瘢痕相关室性心动过速领域，他对梗死瘢痕电图进行特征描述并确定其与折返环路关系的工作，促成了如今常用的基质标测技术的发展。他对记录技术细节的关注有助于确立电生理研究的标准。他的研究并不局限于室性心律失常，而是涵盖了心脏电生理学的各个方面。他是一位卓越的观察者，有识别细微、意外事件并深入探究其潜在机制和意义的天赋。
