Belekhova M G, Kenigfest N B, Chernigovskaya E V, Veselkin N P
Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia.
National Museum of Natural History, Paris, France.
Dokl Biol Sci. 2017 Mar;473(1):80-83. doi: 10.1134/S0012496617020016. Epub 2017 May 16.
We have studied the distribution of calcium-binding proteins in the magnocellular neurosecretory nuclei of nonapeptidergic neurosecretory nuclei of the preoptic-hypothalamic complex in a tortoise (Testudo horsfieldi) and a pond turtle (Emys orbicularis) using immunohistochemistry. We have found that different types of cells in the paraventricular and supraoptic nuclei predominantly express calbindin and, to a lesser extent, calretinin, but not parvalbumin. The selective calbindin/calretinin control of the neurohormone secretion in these hypothalamic nuclei is an evolutionary conservative feature typical of reptiles and mammals.
我们运用免疫组织化学方法，研究了陆龟（印度星龟）和水龟（欧洲泽龟）视前区 - 下丘脑复合体中九肽能神经分泌核团的大细胞神经分泌核内钙结合蛋白的分布情况。我们发现，室旁核和视上核中的不同类型细胞主要表达钙结合蛋白，其次是钙视网膜蛋白，但不表达小白蛋白。这些下丘脑核团中神经激素分泌的钙结合蛋白/钙视网膜蛋白选择性调控是爬行动物和哺乳动物典型的进化保守特征。
