从菲律宾灵芝子实体中分离出的两种新化合物。
Two new compounds from the fruiting bodies of Ganoderma philippii.
作者信息
Yang Shuang, Ma Qing-Yun, Kong Fan-Dong, Xie Qing-Yi, Huang Sheng-Zhuo, Zhou Li-Man, Dai Hao-Fu, Yu Zhi-Fang, Zhao You-Xing
机构信息
a Key Laboratory of Biology and Genetic Resources of Tropical Crops, Institute of Tropical Bioscience and Biotechnology , Chinese Academy of Tropical Agricultural Sciences , Haikou 571101 , China.
b College of Food Science and Technology , Nanjing Agricultural University , Nanjing 210095 , China.
出版信息
J Asian Nat Prod Res. 2018 Mar;20(3):249-254. doi: 10.1080/10286020.2017.1326911. Epub 2017 May 16.
Two new compounds, philippin (1) and 3β,9α,14α-trihydroxy-(22E,24R)-ergost-22-en-7-one (2), were isolated from the fruiting bodies of Ganoderma philippii. Their structures were elucidated on the basis of the spectroscopic technologies, including 1D and 2D NMR as well as MS. The bioassay of inhibitory activity against acetylcholinesterase (AChE) showed compound 1 exhibited weak inhibitory activity against AChE.
从菲律宾灵芝子实体中分离出两种新化合物，菲律宾菌素（1）和3β,9α,14α-三羟基-(22E,24R)-麦角甾-22-烯-7-酮（2）。基于包括一维和二维核磁共振以及质谱在内的光谱技术对它们的结构进行了阐明。对乙酰胆碱酯酶（AChE）抑制活性的生物测定表明化合物1对AChE表现出较弱的抑制活性。
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