Suzuki Ryuji, Abe Takehiko, Uchida Hiroji, Niikura Kazuhiko
Department of Internal Medicine, Hitotsubashi Hospital, 1-2-25 Gakuen Nishimachi, Kodaira-shi, Tokyo, 187-0045, Japan.
Department of Radiology, Japan Anti-Tuberculosis Association, Fukujuji Hospital, 3-1-24 Matsuyama, Kiyoshe-shi, Tokyo, 204-8522, Japan.
CEN Case Rep. 2015 May;4(1):90-94. doi: 10.1007/s13730-014-0146-x. Epub 2014 Oct 18.
Bilateral emphysematous pyelonephritis (EPN) has seldom been reported in patients on maintenance hemodialysis (HD). Percutaneous catheter drainage (PCD) or nephrectomy is often required in the treatment of bilateral EPN because of its poor response to antimicrobial agents and high mortality rate. We report a patient with bilateral EPN on maintenance HD. An octogenarian man with diabetes mellitus who had previously undergone regular HD for 22 months was admitted to our hospital because of severe inflammation resulting from bilateral EPN. His lesions of EPN had resulted in abscess formation in both kidneys and right and left side retroperitoneal space. As patient refused interventional therapy including nephrectomy or PCD, he was treated conservatively. After treatment with several antimicrobial agents for 50 days, he completely recovered from bilateral EPN. To our knowledge, this is the first case report of successful conservative management (antimicrobial therapy alone) of bilateral EPN that developed in a chronic diabetic HD patient.
双侧气肿性肾盂肾炎(EPN)在维持性血液透析(HD)患者中鲜有报道。由于双侧EPN对抗菌药物反应不佳且死亡率高,治疗时通常需要进行经皮导管引流(PCD)或肾切除术。我们报告一例维持性HD患者发生双侧EPN的病例。一名患有糖尿病的八旬男性,此前已规律进行HD治疗22个月,因双侧EPN导致的严重炎症入住我院。他的EPN病变已导致双肾及左右侧腹膜后间隙形成脓肿。由于患者拒绝包括肾切除术或PCD在内的介入治疗,故对其进行保守治疗。在使用多种抗菌药物治疗50天后,他从双侧EPN中完全康复。据我们所知,这是首例关于慢性糖尿病HD患者发生双侧EPN后成功进行保守治疗(仅抗菌治疗)的病例报告。