Leland Hyuma A, Rounds Alexis D, Burtt Karen E, Gould Daniel J, Marecek Geoffrey S, Alluri Ram K, Patel Ketan M, Carey Joseph N
Division of Plastic and Reconstructive Surgery, Keck School of Medicine of USC, Los Angeles, California.
Department of Orthopaedic Surgery, Keck School of Medicine of USC, Los Angeles, California.
Microsurgery. 2018 Mar;38(3):259-263. doi: 10.1002/micr.30176. Epub 2017 May 16.
Tibial fracture management may be complicated by infection of internal fixation hardware (iIFH) resulting in increased morbidity and amputation rate. When iIFH removal is not possible, salvage of the lower extremity is attempted through debridement, antibiotics, and vascularized soft tissue coverage. This study investigates lower extremity salvage with retention of iIFH.
Demographics, outcomes, and bacterial speciation in patients with tibial fractures at a level 1 trauma center from 2007 to 2014 were reviewed. The primary outcome was infection suppression, while secondary outcomes included limb salvage, amputation, and osseous union.
Twenty-five patients underwent soft tissue reconstruction for salvage of iIFH. Average age was 41, 19 (76%) were male, average BMI 30.1 kg/m , 10 (40%) patients smoked. Tibial fractures were closed in 8 (32%), Gustilo-Anderson grade I in 1 (4%), II in 8 (32%), IIIb in 5 (20%), and IIIc in 1 (4%). Staphylococcus was most commonly cultured with 11 (44%) demonstrating methicillin-resistance. Soft tissue reconstruction was performed by local flap in 15 (60%) and free flap in 10 (40%). At an average of 16.1 months, 19 (76%) hardware salvage patients demonstrated clinical suppression of infection, 11 of 19 (57.9%) patients had bony union, and 24 (96%) maintained a salvaged limb. One patient was amputated for recurrent infection.
Following complex, infected tibial fractures, salvage of the lower extremity may be attempted even when iIFH cannot be removed. Thorough debridement, antibiotics, and vascularized soft tissue may suppress infection long enough to facilitate osseous union and subsequent removal of iIFH.
胫骨骨折的治疗可能因内固定器械感染(iIFH)而变得复杂,这会导致发病率增加和截肢率上升。当无法取出iIFH时,通过清创、使用抗生素和带血管蒂软组织覆盖来尝试挽救下肢。本研究调查保留iIFH情况下的下肢挽救情况。
回顾了2007年至2014年在一级创伤中心的胫骨骨折患者的人口统计学资料、治疗结果和细菌种类。主要结果是感染得到控制,次要结果包括肢体挽救、截肢和骨愈合。
25例患者接受了软组织重建以挽救iIFH。平均年龄为41岁,19例(76%)为男性,平均体重指数为30.1kg/m²,10例(40%)患者吸烟。8例(32%)胫骨骨折为闭合性骨折,1例(4%)为Gustilo-Anderson I级,8例(32%)为II级,5例(20%)为IIIb级,1例(4%)为IIIc级。最常培养出的细菌是葡萄球菌,其中11例(44%)表现为耐甲氧西林。15例(60%)采用局部皮瓣进行软组织重建,10例(40%)采用游离皮瓣。平均16.1个月时,19例(76%)保留内固定器械的患者感染得到临床控制,19例中的11例(57.9%)患者实现了骨愈合,24例(96%)患者保住了肢体。1例患者因反复感染而截肢。
在复杂的感染性胫骨骨折后,即使无法取出iIFH,也可尝试挽救下肢。彻底清创、使用抗生素和带血管蒂软组织可能足以控制感染,以促进骨愈合并随后取出iIFH。