Meek Keith M
Structural Biophysics Research Group, School of Optometry and Vision Sciences, Cardiff University, Maindy Road, Cardiff, CF24 4LU, UK.
Biophys Rev. 2009 Jul;1(2):83-93. doi: 10.1007/s12551-009-0011-x. Epub 2009 Jun 6.
Corneal collagen has a number of properties that allow it to fulfil its role as the main structural component within the tissue. Fibrils are narrow, uniform in diameter and precisely organised. These properties are vital to maintain transparency and to provide the biomechanical prerequisites necessary to sustain shape and provide strength. This review describes the structure and arrangement of corneal collagen from the nanoscopic to the macroscopic level, and how this relates to the maintenance of the form and transparency of the cornea.
角膜胶原蛋白具有多种特性,使其能够作为组织内的主要结构成分发挥作用。纤维细且直径均匀,排列精确。这些特性对于维持透明度以及提供维持形状和强度所需的生物力学前提条件至关重要。本综述描述了从纳米级到宏观层面角膜胶原蛋白的结构和排列,以及这与角膜形态和透明度维持的关系。