双侧睾丸肿瘤的肿瘤睾丸精子提取术（onco-TESE）：两例病例报告
Onco-testicular sperm extraction (onco-TESE) for bilateral testicular tumors: two case reports.
作者信息
Tsutsumi Sohgo, Kawahara Takashi, Takeshima Teppei, Chiba Sawako, Uemura Koichi, Otani Masako, Shimokihara Kota, Hayashi Yutaro, Mochizuki Taku, Takamoto Daiji, Hattori Yusuke, Teranishi Jun-Ichi, Miyoshi Yasuhide, Yao Masahiro, Inayama Yoshiaki, Yumura Yasushi, Uemura Hiroji
机构信息
Department of Urology/Renal Transplantation, Yokohama City University Medical Center, Yokohama, Japan.
Reproduction Center, Department of Urology, Yokohama City University Medical Center, Yokohama, Japan.
出版信息
J Med Case Rep. 2017 May 17;11(1):139. doi: 10.1186/s13256-017-1303-6.
BACKGROUND
Most patients with testicular cancer are infertile; thus, the preservation of the sperm after surgery is an important factor to consider. We report two cases of bilateral testicular cancer in patients who underwent bilateral higher orchiectomy and simultaneous testicular sperm extraction.
CASE PRESENTATION
Two Asian-Japanese men were referred to our hospital with bilateral testicular tumors. Both of the patients were preoperatively diagnosed with azoospermia and requested testicular sperm extraction at the time of higher orchiectomy. In one patient, sperm was successfully harvested and then frozen. In the other patient, sperm could not be retrieved from the patient's testis. In both patients, the pathological diagnosis was seminoma. Testicular tumors often occur in patients of reproductive age. The preservation of sperm before chemotherapy or bilateral orchiectomy is necessary for patients with testicular tumors who wish to be fathers.
CONCLUSIONS
Onco-testicular sperm extraction might be an option for patients with testicular cancer and azoospermia or severe oligospermia.
背景
大多数睾丸癌患者会出现不育；因此，术后保留精子是一个需要考虑的重要因素。我们报告了两例双侧睾丸癌患者，他们接受了双侧高位睾丸切除术并同时进行了睾丸精子提取。
病例介绍
两名亚洲日本男性因双侧睾丸肿瘤转诊至我院。两名患者术前均被诊断为无精子症，并在高位睾丸切除术时要求进行睾丸精子提取。其中一名患者成功采集到精子并冷冻保存。另一名患者未能从其睾丸中获取精子。两名患者的病理诊断均为精原细胞瘤。睾丸肿瘤常发生于育龄期患者。对于希望成为父亲的睾丸肿瘤患者，在化疗或双侧睾丸切除术前保留精子是必要的。
结论
对于患有睾丸癌且无精子症或严重少精子症的患者，肿瘤睾丸精子提取可能是一种选择。
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