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睾丸癌男性的生育相关考量

Fertility considerations in men with testicular cancer.

作者信息

Parekh Neel V, Lundy Scott D, Vij Sarah C

机构信息

Department of Urology, Cleveland Clinic, Cleveland, OH, USA.

出版信息

Transl Androl Urol. 2020 Jan;9(Suppl 1):S14-S23. doi: 10.21037/tau.2019.08.08.

Abstract

The modern approach to cancer management has evolved into a multidisciplinary initiative focused not only on cancer specific and overall survival, but also patient quality of life and survivorship. Future fertility is often a major concern for young patients undergoing cancer therapy. Fertility preservation has emerged as a viable but significantly underutilized option. Patients and families should be aware of the varying effects of antineoplastic therapy on their future fertility to allow for an informed decision regarding their fertility preservation options. In this review we discuss the epidemiology, pathophysiology, and management of fertility in the setting of testicular cancer diagnosis and treatment.

摘要

现代癌症管理方法已发展成为一项多学科举措,不仅关注癌症特异性生存率和总生存率,还关注患者的生活质量和生存情况。对于接受癌症治疗的年轻患者来说,未来的生育能力往往是一个主要担忧。生育力保存已成为一种可行但未得到充分利用的选择。患者及其家属应了解抗肿瘤治疗对其未来生育能力的不同影响,以便就生育力保存方案做出明智的决定。在这篇综述中,我们讨论了睾丸癌诊断和治疗背景下生育能力的流行病学、病理生理学和管理。

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