Kovalenko A N
Ter Arkh. 1988;60(9):52-7.
Serum basal concentrations of testosterone, estradiol, and androstenedione, FSH, LH, prolactin, ACTH and cortisol were studied in healthy persons, CHD patients aged 60-89, and in healthy persons aged 20-35 (controls). In some persons of each group a study was made of changes in the concentration of blood prolactin. ACTH, cortisol and urinary excretion of free cortisol as a result of bicycle ergometry exercise testing (submaximum in healthy persons and threshold in patients). A conclusion was made that "endocrinological age" of these hormonal systems in CHD patients aged 60-89 was older than in healthy persons of similar age, and hormonal imbalance continued to be a risk factor at late stages of life.
对健康人、60 - 89岁的冠心病患者以及20 - 35岁的健康人（对照组）的血清睾酮、雌二醇、雄烯二酮、促卵泡激素（FSH）、促黄体生成素（LH）、催乳素、促肾上腺皮质激素（ACTH）和皮质醇的基础浓度进行了研究。在每组的一些人身上，对自行车测力计运动测试（健康人进行次最大强度测试，患者进行阈值测试）后血液催乳素、ACTH、皮质醇浓度以及游离皮质醇的尿排泄变化进行了研究。得出的结论是，60 - 89岁冠心病患者这些激素系统的“内分泌年龄”比同龄健康人要大，而且激素失衡在生命后期仍是一个风险因素。
