Lauffer David Cédric, Lang Florian Johann Werner, Kueng Marc, Allal Abdelkarim Said
aDepartment of Radiation Oncology, HFR - Hôpital Fribourgeois, Fribourg, Switzerland.
bDepartment of Otorhinolaryngology - Head and Neck Surgery, HFR - Hôpital Fribourgeois, Fribourg, Switzerland.
Case Rep Oncol. 2017 Apr 6;10(1):316-320. doi: 10.1159/000470831. eCollection 2017 Jan-Apr.
Brain and Head and neck metastases are rare in prostatic carcinoma patients. In this report we present a very uncommon case of the concomitant occurrence of a prostatic adenocarcinoma with neck metastases and an advanced laryngeal squamous cell carcinoma without neck metastases. The presence of cervical lymph node prostate adenocarcinoma metastasis concomitantly with a laryngeal squamous cell carcinoma is at least intriguing and may remind us of a rare event called "collision tumors". In this case we had the metastatization of 1 carcinoma to the site of the drainage of another carcinoma, but we never found the 2 histological types as close as requested to reach the definition of a collision tumor. This emphasizes the need of histological verification of different sites of recurrence when 2 or more primary cancers are known in a patient, particularly when the treatments of those primary cancers vary widely.
脑转移以及头颈部转移在前列腺癌患者中较为罕见。在本报告中,我们呈现了一例非常罕见的病例,一名前列腺腺癌患者同时出现颈部转移,且患有晚期喉鳞状细胞癌但无颈部转移。颈部淋巴结前列腺腺癌转移与喉鳞状细胞癌同时存在,这至少令人感到好奇,可能会让我们联想到一种罕见的情况,即“碰撞瘤”。在该病例中,一种癌转移至另一种癌的引流部位,但我们从未发现两种组织学类型紧密到足以达到碰撞瘤的定义。这强调了在患者已知患有两种或更多原发性癌症时,尤其是这些原发性癌症的治疗方法差异很大时,对不同复发部位进行组织学验证的必要性。