Tanita Kayo, Fujimura Taku, Sato Yota, Hidaka Takanori, Furudate Sadanori, Kambayashi Yumi, Tsukada Akira, Hashimoto Akira, Aiba Setsuya
Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Case Rep Oncol. 2017 Apr 6;10(1):328-332. doi: 10.1159/000468981. eCollection 2017 Jan-Apr.
Acquired ichthyosis (AI) is a reactive cutaneous manifestation that can be associated with malignant hematological disease, including cutaneous T-cell lymphoma (CTCL). Since it is difficult to distinguish AI from ichthyosiform mycosis fungoides, to select the treatment for CTCL with ichthyosis-like appearance and to evaluate its efficacy is sometimes challenging. In this report, we describe a case of primary cutaneous peripheral T-cell lymphoma not otherwise specified presenting AI successfully treated with oral bexarotene. In the present case, the administration of oral bexarotene was not only effective for lymphoma cells infiltrating ulcers and nodules, but it also eliminated AI.
获得性鱼鳞病（AI）是一种反应性皮肤表现，可与恶性血液系统疾病相关，包括皮肤T细胞淋巴瘤（CTCL）。由于难以将AI与蕈样肉芽肿性鱼鳞病相区分，因此对于具有鱼鳞病样外观的CTCL选择治疗方法并评估其疗效有时具有挑战性。在本报告中，我们描述了一例原发性皮肤外周T细胞淋巴瘤（未另行分类）伴AI的病例，该病例通过口服贝沙罗汀成功治愈。在本病例中，口服贝沙罗汀不仅对浸润溃疡和结节的淋巴瘤细胞有效，还消除了AI。
