Hevey David, Thomas Kevin, Laureano-Schelten Sofia, Looney Karen, Booth Richard
School of Psychology, Trinity College DublinDublin, Ireland.
Department of Psychology, University of BournemouthBournemouth, UK.
Front Psychol. 2017 May 2;8:670. doi: 10.3389/fpsyg.2017.00670. eCollection 2017.
Depression is associated with altered sensitivity to reward and punishment, which can influence complex decision-making. We examined punishment sensitivity in the performance of participants with major depressive disorder (MDD) with that of a comparison group on the automatic Balloon Analogue Risk Task (BART), which is a direct measure of risk taking. The present study examined the BART performance of 30 individuals with MDD and 30 matched comparison individuals. The comparison group ( = 63.25) entered a significantly ( < 0.001; = 1.1) higher number of pumps on the BART than the MDD group ( = 50.83). Higher levels of depression symptoms were significantly correlated ( = -0.40, < 0.05) with entering a lower number of pumps in the MDD group. MDD patients showed an increased sensitivity to punishment on the BART: after a loss, the MDD group decreased ( = 13.7) the number of subsequent pumps they entered by a significantly ( < 0.001, = 0.81) greater amount than the comparison group ( = 4.35). This difference applied to losses only: no difference was found between the groups regarding the magnitude of change in pumps selected after a win. Findings suggest the presence of elevated punishment sensitivity among individuals with MDD, which may contribute to the maintenance of depressive symptoms.
抑郁症与对奖励和惩罚的敏感性改变有关,这会影响复杂的决策。我们在自动气球模拟风险任务(BART)中,将重度抑郁症(MDD)患者与对照组的惩罚敏感性进行检验对比,该任务是对冒险行为的直接测量。本研究对30名MDD患者和30名匹配的对照个体的BART表现进行了检验。对照组(均值 = 63.25)在BART上充气的次数显著多于MDD组(均值 = 50.83)(P < 0.001;效应量 = 1.1)。在MDD组中,抑郁症状水平越高,充气次数越少,二者显著相关(r = -0.40,P < 0.05)。MDD患者在BART上对惩罚的敏感性增加:在一次损失后,MDD组后续充气次数减少(均值 = 13.7),减少幅度显著大于对照组(均值 = 4.35)(P < 0.001,效应量 = 0.81)。这种差异仅适用于损失情况:在获胜后所选充气次数的变化幅度上,两组之间未发现差异。研究结果表明,MDD患者存在惩罚敏感性升高的情况,这可能导致抑郁症状持续存在。