Department of Medicine, Division of Gastroenterology, Los Angeles, CA.
Department of Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Liver Transpl. 2017 Sep;23(9):1153-1160. doi: 10.1002/lt.24789.
The Braden Scale is a standardized tool to assess pressure ulcer risk that is reported for all hospitalized patients in the United States per requirements of the Center for Medicare and Medicaid Services. Previous data have shown the Braden Scale can predict both frailty and mortality risk in patients with decompensated cirrhosis. Our aim was to evaluate the association of the Braden Scale score with short-term outcomes after liver transplantation (LT). We performed a retrospective cohort study of deceased donor LT recipients at 2 centers and categorized them according to the Braden Scale at hospital admission as low (>18), moderate (16-18), or high risk (<16) for pressure ulcer. We created logistic and Poisson multiple regression models to evaluate the association of Braden Scale category with in-hospital and 90-day mortality, length of stay (LOS), nonambulatory status at discharge, and discharge to a rehabilitation facility. Of 341 patients studied, 213 (62.5%) were low risk, 59 (17.3%) were moderate risk, and 69 (20.2%) were high risk. Moderate- and high-risk patients had a greater likelihood for prolonged LOS, nonambulatory status, and discharge to a rehabilitation facility, as compared with low-risk patients. High-risk patients additionally had increased risk for in-hospital and 90-day mortality after LT. Multiple regression modeling demonstrated that high-risk Braden Scale score was associated with prolonged LOS (IRR, 1.56; 95% confidence interval [CI], 1.47-1.65), nonambulatory status at discharge (odds ratio [OR], 4.15; 95% CI, 1.77-9.71), and discharge to a rehabilitation facility (OR, 5.51; 95% CI, 2.57-11.80). In conclusion, the Braden Scale, which is currently assessed in all hospitalized patients in the United States, independently predicted early disability-related outcomes and greater LOS after LT. Liver Transplantation 23 1153-1160 2017 AASLD.
布雷登评分量表是一种评估压疮风险的标准化工具,根据美国医疗保险和医疗补助服务中心的要求,报告所有住院患者的压疮风险。先前的数据表明,布雷登评分量表可以预测失代偿性肝硬化患者的脆弱性和死亡率风险。我们的目的是评估布雷登评分量表与肝移植(LT)后短期结局的关系。我们对 2 个中心的已故供体 LT 受者进行了回顾性队列研究,并根据入院时的布雷登评分量表将他们分为低危(>18)、中危(16-18)或高危(<16)压疮风险。我们创建了逻辑和泊松多重回归模型,以评估布雷登评分量表类别与住院和 90 天死亡率、住院时间(LOS)、出院时不能行走状态以及出院到康复机构之间的关系。在 341 名研究患者中,213 名(62.5%)为低危,59 名(17.3%)为中危,69 名(20.2%)为高危。与低危患者相比,中危和高危患者的 LOS 延长、不能行走状态和出院到康复机构的可能性更大。高危患者在 LT 后还具有更高的住院和 90 天死亡率风险。多回归模型表明,高危布雷登评分量表与 LOS 延长(IRR,1.56;95%置信区间[CI],1.47-1.65)、出院时不能行走状态(比值比[OR],4.15;95%CI,1.77-9.71)和出院到康复机构(OR,5.51;95%CI,2.57-11.80)相关。总之,目前在美国所有住院患者中评估的布雷登评分量表独立预测了 LT 后与残疾相关的早期结局和更长的 LOS。