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[以子宫内膜黏液癌为例探讨苗勒管上皮衍生物中的黏液形成]

[Mucus formation in epithelial derivations of Müller's canal as exemplified by mucinous cancer of the endometrium].

作者信息

Karseladze A I

出版信息

Arkh Patol. 1988;50(10):33-7.

PMID:2851298
Abstract

Analysis of the structural features of mucinous adenocarcinoma of the endometrium and of a large reference group including the hyperplastic and neoplastic processes in the endometrium, specimens of human embryos and fetuses, enabled the authors to come to a conclusion that mucus production and deposition in the endometrial cell cytoplasm is embryogenetically predetermined, though it is restricted in health. During a pathological hyperplasia and malignant degeneration the capacity of such production may recover and induce the formation of the foci of endocervical metaplasia as well as a mucinous adenocarcinoma of the endometrium. The existence of this nosological entity may serve as an argument in favour of the ovarian mucinous tumors origination from the epithelium of the Mullerian canal.

摘要

对子宫内膜黏液腺癌的结构特征以及一个大型参考组进行分析,该参考组包括子宫内膜的增生和肿瘤形成过程、人类胚胎和胎儿的标本,这使作者得出结论:子宫内膜细胞质中黏液的产生和沉积在胚胎发生上是预先确定的,尽管在健康状态下受到限制。在病理性增生和恶性变性过程中,这种产生能力可能恢复,并诱导宫颈化生灶以及子宫内膜黏液腺癌的形成。这种疾病实体的存在可能支持卵巢黏液性肿瘤起源于苗勒管上皮的观点。

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Arkh Patol. 1988;50(10):33-7.
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