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资源匮乏地区的孕产妇严重并发症病例

Maternal near miss in low-resource areas.

作者信息

Goldenberg Robert L, Saleem Sarah, Ali Sumera, Moore Janet L, Lokangako Adrien, Tshefu Antoinette, Mwenechanya Musaku, Chomba Elwyn, Garces Ana, Figueroa Lester, Goudar Shivaprasad, Kodkany Bhalachandra, Patel Archana, Esamai Fabian, Nsyonge Paul, Harrison Margo S, Bauserman Melissa, Bose Carl L, Krebs Nancy F, Hambidge K Michael, Derman Richard J, Hibberd Patricia L, Liechty Edward A, Wallace Dennis D, Belizan Jose M, Miodovnik Menachem, Koso-Thomas Marion, Carlo Waldemar A, Jobe Alan H, McClure Elizabeth M

机构信息

Department of Obstetrics and Gynecology, Columbia University School of Medicine, New York, NY, USA.

Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan.

出版信息

Int J Gynaecol Obstet. 2017 Sep;138(3):347-355. doi: 10.1002/ijgo.12219. Epub 2017 Jun 13.

Abstract

OBJECTIVE

To describe the Global Network Near-Miss Maternal Mortality System and its application in seven sites.

METHODS

In a population-based study, pregnant women eligible for enrollment in the Maternal and Newborn Health Registry at seven sites (Democratic Republic of the Congo; Guatemala; Belagavi and Nagpur, India; Kenya; Pakistan; and Zambia) between January 2014 and April 2016 were screened to identify those likely to have a near-miss event. The WHO maternal near-miss criteria were modified for low-resource settings. The ratio of near-miss events to maternal deaths was calculated.

RESULTS

Among 122 707 women screened, 18 307 (15.0%) had a potential near-miss event, of whom 4866 (26.6%; 4.0% of all women) had a near-miss maternal event. The overall maternal mortality ratio was 155 per 100 000 live births. The ratio of near-miss events to maternal deaths was 26 to 1. The most common factors involved in near-miss cases were the hematologic/coagulation system, infection, and cardiovascular system.

CONCLUSION

By using the Global Network Near-Miss Maternal Mortality System, large numbers of women were screened for near-miss events, including those delivering at home or a low-level maternity clinic. The 4.0% incidence of near-miss maternal mortality is similar to previously reported data. The ratio of 26 near-miss cases to 1 maternal death suggests that near miss might evaluate the impact of interventions more efficiently than maternal mortality.

摘要

目的

描述全球孕产妇险些死亡事件网络系统及其在七个地点的应用情况。

方法

在一项基于人群的研究中,对2014年1月至2016年4月期间七个地点(刚果民主共和国、危地马拉、印度贝拉尔加维和那格浦尔、肯尼亚、巴基斯坦和赞比亚)符合纳入孕产妇和新生儿健康登记条件的孕妇进行筛查,以确定那些可能发生险些死亡事件的孕妇。针对资源匮乏地区对世界卫生组织孕产妇险些死亡标准进行了修改。计算了险些死亡事件与孕产妇死亡的比例。

结果

在筛查的122707名妇女中,18307名(15.0%)有潜在的险些死亡事件,其中4866名(26.6%;占所有妇女的4.0%)发生了孕产妇险些死亡事件。孕产妇总体死亡率为每10万例活产155例。险些死亡事件与孕产妇死亡的比例为26比1。险些死亡病例中最常见的因素涉及血液学/凝血系统、感染和心血管系统。

结论

通过使用全球孕产妇险些死亡事件网络系统,对大量妇女进行了险些死亡事件筛查,包括那些在家中或低级别产科诊所分娩的妇女。孕产妇险些死亡率4.0%与先前报告的数据相似。26例险些死亡病例与1例孕产妇死亡的比例表明,险些死亡事件可能比孕产妇死亡更有效地评估干预措施的影响。

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