Tang Jian, Fan Jin, Yao Yilun, Cai Weihua, Yin Guoyong, Zhou Wei
Department of Orthopaedic, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Medicine (Baltimore). 2017 May;96(20):e6844. doi: 10.1097/MD.0000000000006844.
This study aimed to investigate the perioperative analgesic effect of a buprenorphine transdermal patch in patients who underwent simple lumbar discectomy.In total, 96 patients were randomly divided into parecoxib intravenous injection (Group A), oral celecoxib (Group B), and buprenorphine transdermal patch groups (Group C). The pain status, degree of satisfaction, adverse effects, and condition in which the patient received tramadol hydrochloride for uncontrolled pain were recorded on the night before surgery, postoperative day 1, postoperative day 3, and postoperative day 5.The degree of patient satisfaction in Group C was higher than that in Groups A and B, with minimal adverse effects.The buprenorphine transdermal patch had a better perioperative analgesic effect in patients who underwent simple lumbar discectomy.
本研究旨在探讨丁丙诺啡透皮贴剂对接受单纯腰椎间盘切除术患者的围手术期镇痛效果。总共96例患者被随机分为帕瑞昔布静脉注射组（A组）、口服塞来昔布组（B组）和丁丙诺啡透皮贴剂组（C组）。在手术前一晚、术后第1天、术后第3天和术后第5天记录疼痛状况、满意度、不良反应以及患者因疼痛控制不佳而接受盐酸曲马多治疗的情况。C组患者的满意度高于A组和B组，且不良反应最小。丁丙诺啡透皮贴剂对接受单纯腰椎间盘切除术的患者具有更好的围手术期镇痛效果。
