Pizov N A, Pizova N V
Jaroslavl State Medical University, Jaroslavl, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(1. Vyp. 2):70-74. doi: 10.17116/jnevro20171171270-74.
It is shown that in the development of stroke observed sex differences, which manifest themselves both clinically and by laboratory parameters. While men have a higher incidence of stroke for most of his life, a woman in a more advanced age have a higher risk for stroke. Sex differences in the development of stroke depend on several factors, including genetic and hormonal changes throughout life. Studies sex differences in the risk of stroke is only in the initial stage, but the first results show that there are differences in neuronal cell death in males and females after experimental ischemic stroke. A better understanding of the mechanisms underlying the development of stroke in men and women will lead to more appropriate treatment strategies for patients of both sexes.
研究表明，在中风的发展过程中存在性别差异，这在临床和实验室参数方面均有体现。虽然男性在其一生中大部分时间里中风发病率较高，但年龄较大的女性中风风险更高。中风发展过程中的性别差异取决于多种因素，包括一生中的基因和激素变化。关于中风风险的性别差异研究尚处于初始阶段，但初步结果表明，实验性缺血性中风后男性和女性的神经元细胞死亡存在差异。更好地理解男性和女性中风发展的潜在机制将为两性患者带来更合适的治疗策略。
