Maiborodin I V, Agzaev M K, Ragimova T M, Maiborodin I I
Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the RAS, Novosibirsk, 630090, Russian Federation;
Institute of molecular pathology and patomorphology, Novosibirsk, 630117, Russian Federation.
Adv Gerontol. 2016;29(2):229-238.
Numerous and often contradictory research results specify that the mechanism of increased susceptibility to diseases in old age has no satisfactory explanation so far. Together with it in literature almost completely there are no comparative data on features of surgery and injury influence on a structure and functions of lymphoid organs at patients of different age groups. However, lymph nodes are a marker of activity of inflammatory process in the region, on their changes it is possible to estimate precisely productivity of different medical actions, to predict development of many complications, and, thus, successfully to take actions for their prophylaxis. All this is especially important and actual because of constant increase in average age, in life expectancy of human population and strengthening of surgical activity at patients of advanced and old age.
众多且往往相互矛盾的研究结果表明，迄今为止，老年人群疾病易感性增加的机制尚无令人满意的解释。与此同时，文献中几乎完全没有关于不同年龄组患者手术及损伤对淋巴器官结构和功能影响特点的比较数据。然而，淋巴结是该区域炎症过程活动的标志物，通过其变化可以精确评估不同医疗措施的效果，预测许多并发症的发生，从而成功采取预防措施。鉴于人类平均年龄、预期寿命的不断增加以及老年和高龄患者手术活动的加强，所有这些尤为重要且具有现实意义。
