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名字里有什么?为什么这些蛋白质是内在无序的:为什么这些蛋白质是内在无序的。

What's in a name? Why these proteins are intrinsically disordered: Why these proteins are intrinsically disordered.

作者信息

Dunker A Keith, Babu M Madan, Barbar Elisar, Blackledge Martin, Bondos Sarah E, Dosztányi Zsuzsanna, Dyson H Jane, Forman-Kay Julie, Fuxreiter Monika, Gsponer Jörg, Han Kyou-Hoon, Jones David T, Longhi Sonia, Metallo Steven J, Nishikawa Ken, Nussinov Ruth, Obradovic Zoran, Pappu Rohit V, Rost Burkhard, Selenko Philipp, Subramaniam Vinod, Sussman Joel L, Tompa Peter, Uversky Vladimir N

机构信息

Indiana University School of Medicine; Indianapolis, IN USA.

MRC Laboratory of Molecular Biology; Cambridge, UK.

出版信息

Intrinsically Disord Proteins. 2013 Apr 1;1(1):e24157. doi: 10.4161/idp.24157. eCollection 2013 Jan-Dec.

Abstract

"What's in a name? That which we call a rose By any other name would smell as sweet." This article opens a series of publications on disambiguation of the basic terms used in the field of intrinsically disordered proteins. We start from the beginning, namely from the explanation of what the expression "intrinsically disordered protein" actually means and why this particular term has been chosen as the common denominator for this class of proteins characterized by broad structural, dynamic and functional characteristics.

摘要

“名字中有什么?我们称之为玫瑰的,换个名字也同样芬芳。” 本文开启了一系列关于消除内在无序蛋白质领域中基本术语歧义的出版物。我们从一开始讲起,即解释 “内在无序蛋白质” 这个表达实际上是什么意思,以及为什么选择这个特定术语作为这类具有广泛结构、动态和功能特征的蛋白质的通用名称。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/038b/5424803/f86cad96f41f/kidp-01-01-10924157-g001.jpg

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