Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
J Appl Clin Med Phys. 2022 Aug;23(8):e13699. doi: 10.1002/acm2.13699. Epub 2022 Jul 20.
Well-designed routine multileaf collimator (MLC) quality assurance (QA) is important to assure external-beam radiation treatment delivery accuracy. This study evaluates the clinical necessity of a comprehensive weekly (C-Weekly) MLC QA program compared to the American Association of Physics in Medicinerecommended weekly picket fence test (PF-Weekly), based on our seven-year experience with weekly MLC QA.
The C-Weekly MLC QA program used in this study includes 5 tests to analyze: (1) absolute MLC leaf position; (2) interdigitation MLC leaf position; (3) picket fence MLC leaf positions at static gantry angle; (4) minimum leaf-gap setting; and (5) volumetric-modulated arc therapy delivery. A total of 20,226 QA images from 16,855 tests (3,371 tests × 5) for 11 linacs at 5 photon clinical sites from May 2014 to June 2021 were analyzed. Failure mode and effects analysis was performed with 5 failure modes related to the 5 tests. For each failure mode, a risk probability number (RPN) was calculated for a C-Weekly and a PF-Weekly MLC QA program. The probability of occurrence was evaluated from statistical analyses of the C-Weekly MLC QA.
The total number of failures for these 16,855 tests was 143 (0.9%): 39 (27.3%) for absolute MLC leaf position, 13 (9.1%) for interdigitation position, 9 (6.3%) for static gantry picket fence, 2 (1.4%) for minimum leaf-gap setting, and 80 (55.9%) for VMAT delivery. RPN scores for PF-Weekly MLC QA ranged from 60 to 192 and from 48 to 96 for C-Weekly MLC QA.
RPNs for the 5 failure modes of MLC QA tests were quantitatively determined and analyzed. A comprehensive weekly MLC QA is imperative to lower the RPNs of the 5 failure modes to the desired level (<125); those from the PF-Weekly MLC QA program were found to be higher (>125). This supports the clinical necessity for comprehensive weekly MLC QA.
精心设计的常规多叶准直器(MLC)质量保证(QA)对于确保外照射放射治疗的准确性非常重要。本研究根据我们七年来每周 MLC QA 的经验,评估了与美国医学物理学家协会推荐的每周尖桩围栏测试(PF-Weekly)相比,全面每周(C-Weekly)MLC QA 计划的临床必要性。
本研究中使用的 C-Weekly MLC QA 计划包括 5 项测试,用于分析:(1)绝对 MLC 叶片位置;(2)交错 MLC 叶片位置;(3)静态机架角度的尖桩围栏 MLC 叶片位置;(4)最小叶片间隙设置;和(5)容积调制弧形治疗输送。对 2014 年 5 月至 2021 年 6 月来自 5 个光子临床站点的 11 台直线加速器的 3371 次 5 次测试(共 20226 次 QA 图像)进行了分析。对 5 种与 5 种测试相关的失效模式进行了失效模式和影响分析。对于每种失效模式,为 C-Weekly 和 PF-Weekly MLC QA 计划计算了风险概率数(RPN)。通过对 C-Weekly MLC QA 的统计分析评估了发生概率。
这些 16855 次测试的总失败次数为 143(0.9%):39(27.3%)为绝对 MLC 叶片位置,13(9.1%)为交错位置,9(6.3%)为静态机架尖桩围栏,2(1.4%)为最小叶片间隙设置,80(55.9%)为 VMAT 输送。PF-Weekly MLC QA 的 RPN 评分范围为 60 至 192,C-Weekly MLC QA 的 RPN 评分范围为 48 至 96。
对 MLC QA 测试的 5 种失效模式的 RPN 进行了定量确定和分析。全面的每周 MLC QA 对于将 5 种失效模式的 RPN 降低到期望水平(<125)至关重要;发现来自 PF-Weekly MLC QA 计划的 RPN 较高(>125)。这支持了全面每周 MLC QA 的临床必要性。