Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
State Key Laboratory of Luminescent Materials and Devices, South China University of Technology , Guangzhou 510640, China.
Org Lett. 2017 Jun 2;19(11):2825-2828. doi: 10.1021/acs.orglett.7b00980. Epub 2017 May 18.
A convenient protocol for the synthesis of sulfonylated benzofurans via Ag-catalyzed oxidative cyclization has been established. Chemically stable and easily available sodium sulfinates were used as the sulfonylation reagents and building block for the heterocycle construction. With this novel strategy, various benzofurans bearing dual functional groups could be obtained in good yields with high chemo- and regioselectivities under mild conditions.
建立了一种通过 Ag 催化氧化环化合成磺酰化苯并呋喃的方便方法。化学稳定且易于获得的亚磺酸钠被用作磺酰化试剂和杂环构建的构建块。使用这种新策略，在温和条件下，以高化学和区域选择性得到了各种带有双官能团的苯并呋喃，产率良好。
