Bukreyeva Iryna, Angoulvant Adela, Bendib Inès, Gagnard Jean-Charles, Bourhis Jean-Henri, Dargère Sylvie, Bonhomme Julie, Thellier Marc, Gachot Bertrand, Wyplosz Benjamin
Emerg Infect Dis. 2017 Jun;23(6):1039-1041. doi: 10.3201/eid2306.161825.
Enterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but without major adverse events. Modifications of immunosuppression could be avoided when E. bieneusi is rapidly identified and fumagillin therapy is started promptly.
肠微孢子虫病是免疫功能低下患者中一种新出现的疾病。我们报告了2例异基因造血干细胞移植患者发生这种疾病,经烟曲霉素成功治疗。出现了血小板减少症,但未发生重大不良事件。当迅速识别出肠微孢子虫并及时开始烟曲霉素治疗时,可以避免免疫抑制的调整。