Zeidan O, Zheng Y
ProCure Treatment Centers, Oklahoma City, OK.
Med Phys. 2012 Jun;39(6Part21):3865. doi: 10.1118/1.4735781.
An overview of current status of clinical proton dosimetry is presented. Absolute dosimetry in proton beams using IAEA TRS 398 and ICRU 59 dosimetry protocols is presented. An overview of the use of various detectors for proton therapy beam characterization is presented including Ion Chambers for point measurements, Multi-Layer Ionization Chambers (MLICs) for percentage depth dose (PDD) measurements, and other types of detectors such as TLDs and diodes. The use of ID and 2D commercial arrays for routine dosimetry for performing daily output, range verification, symmetry, and flatness is also presented. Some of the challenges in the design and performance of certain detectors related to LET quenching effects is discussed. The use of film (radiographic and radiochromic) for various beam QA tasks is discussed. Current status and prospects of 3D dosimetry for particle therapy is also presented. Specific challenges in quality assurance with certain beam delivery technologies are also discussed such as pencil beams, scattered beams, and uniform scanning beams. Proton machine QA checks such as daily, monthly, and annual QA, as well as patient specific proton beam QA are presented.
介绍了临床质子剂量测定的现状概述。介绍了使用国际原子能机构(IAEA)TRS 398和国际辐射单位与测量委员会(ICRU)59剂量测定协议进行质子束绝对剂量测定的方法。概述了使用各种探测器进行质子治疗束特性表征的情况,包括用于点测量的电离室、用于百分深度剂量(PDD)测量的多层电离室(MLIC)以及其他类型的探测器,如热释光剂量计(TLD)和二极管。还介绍了使用一维(ID)和二维(2D)商业阵列进行常规剂量测定以执行每日输出、射程验证、对称性和平坦度测量的情况。讨论了某些探测器在设计和性能方面与传能线密度(LET)猝灭效应相关的一些挑战。讨论了使用胶片(射线照相和放射变色)进行各种束质量保证(QA)任务的情况。还介绍了粒子治疗三维剂量测定的现状和前景。还讨论了某些束流输送技术在质量保证方面的具体挑战,如笔形束、散射束和均匀扫描束。介绍了质子机器的QA检查,如每日、每月和每年的QA,以及针对患者的特定质子束QA。