两种不同剂量水平的更昔洛韦治疗艾滋病患者巨细胞病毒性脉络膜视网膜炎的疗效与安全性。
Efficacy and safety of two different dose levels of ganciclovir for the treatment of cytomegalovirus chorioretinitis in AIDS patients.
作者信息
Gaub J, Poulsen A G, Pedersen C, Tinning S, Højgaard K, Thomson M H, Faber V, Nielsen J O
机构信息
Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark.
出版信息
Scand J Infect Dis. 1988;20(5):479-82. doi: 10.3109/00365548809032494.
PMID:2851877
Abstract
The effect of different dosages of ganciclovir on proved cytomegalovirus chorioretinitis was tested in a randomized trial on 11 homosexual men with AIDS. The effect of 5 mg/kg/day was as good as 10 mg/kg/day. The lower dosage had less toxicity.
摘要
在一项针对11名患有艾滋病的同性恋男性的随机试验中，测试了不同剂量的更昔洛韦对确诊的巨细胞病毒性脉络膜视网膜炎的疗效。5毫克/千克/天的疗效与10毫克/千克/天的疗效相当。较低剂量的毒性较小。
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