Autosomal Dominant Compelling Helioopthalmic Outburst (ACHOO) Syndrome is characterized by uncontrollable sneezing in response to the sudden exposure to bright light, typically intense sunlight (1). This type of sneezing is also known as photic sneezing. About one in four individuals who already have a prickling sensation in their nose will sneeze in response to sunlight, but “pure” photic sneezing is far less common (2). Sneezing is usually triggered by contact with infectious agents or after inhaling irritants, but the cause of photic sneezing is not fully understood. It may involve an over-excitability of the visual cortex in response to light, leading to a stronger activation of the secondary somatosensory areas (3).
常染色体显性强迫性日光性喷嚏（ACHOO）综合征的特征是在突然暴露于强光（通常是强烈阳光）下时会 uncontrollable 打喷嚏（1）。这种类型的打喷嚏也被称为光喷嚏反射。已经在鼻子中有刺痛感的个体中，约四分之一会对阳光做出打喷嚏反应，但“纯粹”的光喷嚏反射要少见得多（2）。打喷嚏通常是由与传染原接触或吸入刺激物后引发的，但光喷嚏反射的原因尚未完全了解。它可能涉及视觉皮层对光的过度兴奋，导致二级躯体感觉区的更强激活（3）。 （注：“uncontrollable”原英文拼写有误，正确拼写为“uncontrollable”，翻译为“无法控制的” ）
