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大鼠中枢神经系统中的心房利钠肽

Atrial natriuretic peptide in the central nervous system of the rat.

作者信息

Skofitsch G, Jacobowitz D M

机构信息

Department of Zoology, University of Graz, Austria.

出版信息

Cell Mol Neurobiol. 1988 Dec;8(4):339-91. doi: 10.1007/BF00711224.

Abstract
  1. Studies of the presence of atrial natriuretic peptide immunoreactivity and receptor binding sites in the central nervous system have revealed unusual sites of interest. 2. As a result, numerous studies have appeared that indicate that brain atrial natriuretic peptide is implicated in the regulation of blood pressure, fluid and sodium balance, cerebral blood flow, brain microcirculation, blood-brain barrier function, and cerebrospinal fluid production. 3. Alteration of the atrial natriuretic peptide system in the brain could have important implications in hypertensive disease and disorders of water balance in the central nervous system.
摘要
  1. 对中枢神经系统中心房利钠肽免疫反应性和受体结合位点的研究揭示了一些不同寻常的有趣部位。2. 因此,出现了大量研究表明脑心房利钠肽与血压调节、体液和钠平衡、脑血流量、脑微循环、血脑屏障功能以及脑脊液生成有关。3. 脑中房利钠肽系统的改变可能对高血压疾病和中枢神经系统水平衡紊乱具有重要影响。

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本文引用的文献

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SPECIFIC GRANULES IN ATRIAL MUSCLE CELLS.心房肌细胞中的特殊颗粒。
J Cell Biol. 1964 Oct;23(1):151-72. doi: 10.1083/jcb.23.1.151.
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Fluorescent antibody methods.荧光抗体法
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