Ophthalmology Division, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Retina. 2018 Jul;38(7):1415-1419. doi: 10.1097/IAE.0000000000001711.
To evaluate the rate of epiretinal membrane (ERM) recurrence in eyes that underwent ERM peeling surgery at least 5 years earlier.
Retrospective interventional case series study of 37 patients (15 women and 22 men; mean age, 70 ± 7.6 years) operated on for ERM removal with a follow-up of at least 5 years. The patients underwent testing for visual acuity, an ophthalmic examination, and optical coherence tomography imaging, all of which were assessed preoperatively, postoperatively, and at the 5-year follow-up.
Visual acuity significantly improved at 1 year after peeling compared with baseline (P = 0.045), and the improved results were maintained at 5 years (P = 0.804) 0.766 logarithm of the minimum angle of resolution (Snellen 6/35). The central macular thickness decreased significantly at the 1-year follow-up compared with baseline and continued to decrease as measured at the 5-year follow-up (P = 0.04). At 5 years, the ERM recurrence rate reached 58% (28% extrafoveal). Photoreceptor atrophy and retinal pigment epithelium changes correlated with diabetes mellitus (P = 0.028).
The recurrence rate of ERM after peeling surgery was reported as being around 5% to 12%. It was 58% in the current study. Because the recurrent ERM is generally mild, visual acuity was unaffected.
评估至少 5 年前接受过视网膜内膜(ERM)剥除手术的眼睛中 ERM 复发的比率。
回顾性介入性病例系列研究,纳入了 37 名患者(15 名女性和 22 名男性;平均年龄 70 ± 7.6 岁),均接受了 ERM 切除手术,随访时间至少为 5 年。所有患者均接受了视力、眼科检查和光学相干断层扫描成像检查,所有检查均在术前、术后和 5 年随访时进行评估。
与基线相比,剥除后 1 年视力显著提高(P = 0.045),且 5 年时的改善结果仍保持稳定(P = 0.804)(0.766 对数最小角分辨率(Snellen 6/35))。与基线相比,1 年随访时中央黄斑厚度显著降低,且在 5 年随访时仍持续降低(P = 0.04)。5 年时,ERM 复发率达到 58%(28%为黄斑外)。光感受器萎缩和视网膜色素上皮变化与糖尿病相关(P = 0.028)。
剥除手术后 ERM 的复发率报告约为 5%至 12%。本研究中为 58%。由于复发性 ERM 通常较轻,视力不受影响。