Division of Pharmaceutical and Fine Chemical Technology, Department of Chemical Technology, University of Calcutta, 92, A.P.C. Road, Kolkata 700009, West Bengal, India.
Division of Pharmaceutical and Fine Chemical Technology, Department of Chemical Technology, University of Calcutta, 92, A.P.C. Road, Kolkata 700009, West Bengal, India.
Carbohydr Polym. 2017 Aug 15;170:89-98. doi: 10.1016/j.carbpol.2017.04.056. Epub 2017 Apr 23.
This work relates to guar gum benzoate self assembly nanoparticles synthesis and nano composite films development with gelatin. Guar gum benzoate was synthesized in a Hofmeister cation guided homogeneous phase reaction. Self assembly polysaccharide nanoparticles were prepared in solvent displacement technique. Electron microscopy and DLS study confirmed uniform quasi spherical nanoparticles with ζ-potential - 28.7mV. Nanocomposite films were further developed in gelatin matrix. The film capacity augmenting due to nanoparticles incorporation was noteworthy. Superior barrier properties, reinforcing and thermal insulation effects were observed in films dispersed with 20% w/w nanoparticles. Detailed FTIR studies and thermal analysis confirmed nanoparticles interactions in the film matrix. The nanocomposite film water vapour permeability was at 0.75gmmkPah, thermal conductivity 0.39WmK and the tensile strength were recorded at 3.87MPa. The final film expressed excellent antimicrobial properties against water born gram negative and gram positive bacteria.
这项工作涉及到瓜尔胶苯甲酸酯自组装纳米粒子的合成和与明胶的纳米复合薄膜的开发。在霍夫迈斯特阳离子引导的均相反应中合成了瓜尔胶苯甲酸酯。通过溶剂置换技术制备了自组装多糖纳米粒子。电子显微镜和 DLS 研究证实了具有 ζ 电位-28.7mV 的均匀准球形纳米粒子。纳米复合材料薄膜进一步在明胶基质中开发。由于纳米粒子的掺入，薄膜的容量增加是值得注意的。在分散有 20%w/w 纳米粒子的薄膜中观察到了更好的阻隔性能、增强和隔热效果。详细的傅里叶变换红外光谱研究和热分析证实了纳米粒子在薄膜基质中的相互作用。纳米复合薄膜的水蒸气透过率为 0.75gmmkPah，导热系数为 0.39WmK，拉伸强度为 3.87MPa。最终的薄膜对水生革兰氏阴性和革兰氏阳性细菌表现出优异的抗菌性能。
