Labaude Sophie, Moret Yannick, Cézilly Frank, Reuland Charel, Rigaud Thierry
Université de Bourgogne Franche-Comté, UMR CNRS 6282 Biogéosciences, équipe Ecologie Evolutive, 6 boulevard Gabriel, Dijon, France.
Université de Bourgogne Franche-Comté, UMR CNRS 6282 Biogéosciences, équipe Ecologie Evolutive, 6 boulevard Gabriel, Dijon, France.
Dev Comp Immunol. 2017 Nov;76:25-33. doi: 10.1016/j.dci.2017.05.013. Epub 2017 May 15.
Temperature is known to impact host-parasite interactions in various ways. Such effects are often regarded as the consequence of the increased metabolism of parasites with increasing temperature. However, the effect of temperature on hosts' immune system could also be a determinant. Here we assessed the influence of temperature on the immunocompetence of the crustacean amphipod Gammarus pulex. Amphipods play a key ecological role in freshwater ecosystems that can be altered by several parasites. We investigated the consequences of three weeks of acclimatization at four temperatures (from 9 °C to 17 °C) on different immunological parameters. Temperature influenced both hemocyte concentration and active phenoloxidase enzymatic activity, with lower values at intermediate temperatures, while total phenoloxidase activity was not affected. In addition, the ability of gammarids to clear a bacterial infection was at the highest at intermediate temperatures. These results suggest a dysregulation of the immune system of gammarids in response to stress induced by extreme temperature.
众所周知，温度会以多种方式影响宿主与寄生虫之间的相互作用。此类影响通常被视为寄生虫新陈代谢随温度升高而增加的结果。然而，温度对宿主免疫系统的影响也可能是一个决定性因素。在此，我们评估了温度对甲壳类动物双齿围沙蚕免疫能力的影响。双齿围沙蚕在淡水生态系统中发挥着关键的生态作用，而这一作用可能会受到多种寄生虫的改变。我们研究了在四种温度（从9°C到17°C）下进行三周驯化对不同免疫参数的影响。温度影响了血细胞浓度和活性酚氧化酶的酶活性，中间温度下的值较低，而总酚氧化酶活性未受影响。此外，双齿围沙蚕清除细菌感染的能力在中间温度下最高。这些结果表明，双齿围沙蚕的免疫系统因极端温度引起的应激而失调。
